For procurement managers and R&D scientists in the chemical and pharmaceutical industries, identifying reliable sources for critical intermediates like 6-Hydroxy-5-nitronicotinic acid (CAS: 6635-31-0) is paramount. This pyridine derivative is a highly valued building block, primarily used in organic synthesis for the development of pharmaceuticals and agrochemicals. Understanding its properties and where to procure it efficiently can significantly impact project timelines and product quality.

Understanding 6-Hydroxy-5-nitronicotinic Acid

6-Hydroxy-5-nitronicotinic acid is characterized by its yellow solid appearance and a molecular formula of C6H4N2O5. Its chemical structure, featuring a pyridine ring with hydroxyl, nitro, and carboxylic acid groups, makes it a versatile intermediate for creating complex molecular architectures. Its CAS number, 6635-31-0, is a critical identifier for sourcing and technical specification. The compound's utility stems from its ability to participate in various chemical reactions, allowing for the synthesis of a wide array of biologically active molecules.

Key Applications in Your Industry

The primary applications for 6-Hydroxy-5-nitronicotinic acid lie in its role as a precursor. In the pharmaceutical sector, it is employed in the synthesis of active pharmaceutical ingredients (APIs), contributing to the development of new therapeutic agents. Its potential biological activities, such as antimicrobial and anti-inflammatory properties, make it an attractive starting material for drug discovery programs. For agrochemical development, it serves as a building block for pesticides and herbicides, aiding in the creation of more effective crop protection solutions. Researchers also utilize it as a fundamental component in broader organic synthesis to explore novel compounds and materials.

What to Look for When Buying: Purity and Specifications

When sourcing 6-Hydroxy-5-nitronicotinic acid, paying close attention to product specifications is essential. Manufacturers typically offer the compound with an assay of ≥98.0%. Key physical properties include a melting point range of 269-271°C and a density around 1.7 g/cm³. Information regarding its spectral characteristics, such as NMR and IR data, is crucial for quality control and confirmation of identity. For procurement managers, understanding these specifications ensures that the purchased material meets the stringent requirements of their synthesis processes.

Sourcing Strategies: Finding a Reliable Supplier

Identifying a trustworthy manufacturer and supplier is key to ensuring a consistent supply of high-purity 6-Hydroxy-5-nitronicotinic acid. Companies specializing in fine chemical intermediates and pyridine derivatives are primary targets. When evaluating suppliers, consider their manufacturing capabilities, quality control processes, and commitment to regulatory compliance. Many suppliers offer detailed product documentation, including Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS). For businesses looking to buy in bulk or establish long-term supply agreements, engaging directly with manufacturers or their authorized distributors is advisable to secure competitive pricing and favorable terms. Inquire about lead times, packaging options (e.g., 25 kg drums), and shipping logistics to optimize your procurement process.

Conclusion

6-Hydroxy-5-nitronicotinic acid is an indispensable intermediate for innovation in the pharmaceutical and agrochemical industries. By focusing on purity, detailed specifications, and partnering with reputable suppliers, R&D teams and procurement professionals can effectively leverage this versatile compound to drive their product development forward. If you are looking to purchase this essential chemical, seeking out a reliable manufacturer in China who prioritizes quality and customer service is the optimal strategy.