In the complex world of pharmaceutical manufacturing, the reliable sourcing of high-quality API intermediates is paramount. Among these, 3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile (CAS 276863-95-7) stands out as a critical component, particularly in the synthesis of Vilazodone. For research scientists, formulation chemists, and procurement managers, understanding the significance and sourcing strategies for this compound is essential for successful drug development and production.

As a key intermediate, 3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile plays an indispensable role in the multi-step synthesis of Vilazodone, a selective serotonin reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist used to treat major depressive disorder. The purity and consistency of this intermediate directly impact the efficacy and safety profile of the final Active Pharmaceutical Ingredient (API). Therefore, identifying a dependable manufacturer and supplier who can guarantee a high purity level, typically ≥99%, is a non-negotiable aspect of procurement.

When seeking to buy 3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile, pharmaceutical professionals often look for suppliers based in regions known for their robust chemical manufacturing capabilities, such as China. The ability to secure a stable supply chain, especially for bulk requirements, is critical. Companies engaged in large-scale production need to be confident in the supplier's capacity to deliver consistently without compromising on quality. This involves evaluating the supplier's adherence to stringent quality control measures and their experience in handling pharmaceutical intermediates.

The price of 3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile can vary based on purity, quantity, and the supplier's standing. Procurement managers often conduct thorough market research to identify competitive pricing that aligns with their project budgets. However, it is crucial to balance cost-effectiveness with quality assurance. A slightly higher investment for a product from a trusted manufacturer can prevent costly delays and batch failures down the line.

Furthermore, understanding the applications beyond Vilazodone synthesis is also beneficial. This indole derivative may find utility in other pharmaceutical research endeavors or as an intermediate for different APIs. For those looking for a consistent supply of pharmaceutical building blocks, partnering with a reputable supplier like us ensures access to critical materials. We are dedicated to supporting the pharmaceutical industry by providing high-quality intermediates, fostering innovation, and enabling the development of life-saving medications. Reach out to us to inquire about the availability and pricing of 3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile, and experience a partnership built on reliability and expertise.