In the complex world of pharmaceutical manufacturing, the reliable sourcing of high-purity intermediates is paramount. Ethyl 2-oxo-4-phenylbutyrate (CAS 64920-29-2) stands out as a critical alpha-ketoester, serving as a foundational building block for several essential active pharmaceutical ingredients (APIs). For R&D scientists and procurement managers, understanding the characteristics and sourcing channels for this compound is key to ensuring successful drug development and production.

Ethyl 2-oxo-4-phenylbutyrate, characterized by its light yellow oily liquid appearance and a purity typically exceeding 95-99%, is primarily recognized for its role in synthesizing potent cardiovascular medications like Lisinopril. Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, is widely prescribed for hypertension and heart failure. The precise structure and purity of Ethyl 2-oxo-4-phenylbutyrate directly influence the efficacy and safety of the final API, underscoring the importance of sourcing from reputable manufacturers.

Beyond its application in ACE inhibitors, this versatile intermediate is also crucial for the synthesis of Cilastatin. Cilastatin is an inhibitor of dehydropeptidase I, often used in combination with the antibiotic imipenem to increase its plasma levels and prevent renal toxicity. The demand for Cilastatin highlights the consistent need for a stable supply of its precursor, Ethyl 2-oxo-4-phenylbutyrate.

For procurement professionals looking to buy Ethyl 2-oxo-4-phenylbutyrate, identifying a reliable manufacturer in China is a strategic advantage. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in producing these critical intermediates, offering competitive prices and consistent quality. Their expertise in chemical synthesis and quality control ensures that the product meets the demanding specifications required by the pharmaceutical industry. When you purchase this intermediate, inquire about its assay, impurity profile, and packaging to ensure it aligns with your production requirements.

The synthesis of Ethyl 2-oxo-4-phenylbutyrate itself involves sophisticated organic chemistry techniques. Understanding the production process can also provide insight into potential supply chain resilience. As the pharmaceutical landscape evolves, securing a dependable supplier for key intermediates like Ethyl 2-oxo-4-phenylbutyrate remains a top priority. By partnering with experienced manufacturers, companies can ensure a steady flow of high-quality materials, facilitating the timely delivery of life-saving medications to patients worldwide. If you are seeking this essential pharmaceutical intermediate, consider reaching out to established Chinese chemical suppliers for your bulk requirements.