Procurement managers in the pharmaceutical and fine chemical sectors face the constant challenge of securing high-quality raw materials reliably and cost-effectively. One such critical material is 4-(3,4-Dichlorophenyl)-1-tetralone (CAS 79560-19-3), a vital intermediate primarily used in the synthesis of the widely prescribed antidepressant, Sertraline. This guide aims to equip procurement professionals with the knowledge to navigate the sourcing of this essential chemical.

Understanding Your Needs: Quality and Purity

The foremost consideration when purchasing 4-(3,4-Dichlorophenyl)-1-tetralone for pharmaceutical applications is its purity. Typically specified as 98% minimum, variations in purity can significantly impact downstream synthesis yields, the formation of unwanted by-products, and ultimately, the quality and regulatory compliance of the final API. When evaluating a supplier, always request a detailed Certificate of Analysis (CoA) that specifies the purity and the analytical methods used.

Key Sourcing Criteria for 4-(3,4-Dichlorophenyl)-1-tetralone:

  • Supplier Reliability: Look for manufacturers with a proven track record in producing fine chemical intermediates. Companies that demonstrate consistent quality, robust supply chain management, and adherence to international standards are preferred.
  • Pricing and Quotation: Obtain multiple quotes from reputable suppliers. While price is a significant factor, it should never be the sole determinant. Compare not only the per-kilogram price but also the minimum order quantities (MOQs) and delivery terms.
  • Logistics and Transportation: Understand the Incoterms offered (e.g., FOB, CIF, EXW) and the associated shipping costs and delivery timelines. Reliable logistics partners are crucial for timely delivery, especially for time-sensitive pharmaceutical manufacturing.
  • Regulatory Compliance: Ensure the supplier can provide all necessary documentation, including MSDS, CoA, and any specific regulatory certifications required in your region.
  • Technical Support: A good supplier will offer technical support, answering queries regarding product specifications, handling, and storage.

Where to Find 4-(3,4-Dichlorophenyl)-1-tetralone?

Global manufacturers and suppliers in countries like China are significant sources for this intermediate. When you search to buy 4-(3,4-Dichlorophenyl)-1-tetralone, focusing on established chemical suppliers with dedicated pharmaceutical intermediate divisions will yield the best results. These suppliers often have strong manufacturing capabilities and extensive networks.

For procurement managers seeking a dependable source for high-quality 4-(3,4-Dichlorophenyl)-1-tetralone, understanding these criteria is essential. By prioritizing purity, supplier reliability, and comprehensive support, you can secure a consistent supply of this vital intermediate, thereby ensuring the smooth operation of your pharmaceutical production processes.