For procurement managers navigating the complex landscape of chemical sourcing, identifying high-quality intermediates is paramount. 3-Amino-1,2-Propanediol, also known by its synonym Isoserinol and CAS number 616-30-8, stands out as a critical building block, particularly within the pharmaceutical industry. Its primary application as a key intermediate in the synthesis of non-ionic X-CT contrast agents, such as iohexol, underscores the need for stringent purity and reliable supply.

When considering a purchase, understanding the typical specifications is crucial. High-purity grades, often specified at 99.5% minimum purity by GC, are preferred to ensure the efficacy and safety of the final pharmaceutical products. Other important parameters include assay by titration (typically 98.5% to 101.5%) and strict limits on impurities like glycerol, serinol, and diamino-propanol. For procurement professionals aiming to secure a consistent supply, looking for manufacturers that provide Certificates of Analysis (CoA) with each batch is a best practice.

The global market offers several sources for 3-Amino-1,2-Propanediol. For those looking to buy in China, identifying established suppliers with export experience is key. Factors like years of export experience, verification by third-party inspection agencies, and a track record of serving Fortune 500 companies can indicate a reliable partner. Requesting samples is a standard procedure to verify quality and suitability for your specific application before committing to larger orders. Considering the price per kilogram is, of course, a significant factor, but it should be balanced against the supplier's reputation, quality control, and supply chain stability.

Beyond its role in contrast agents, 3-Amino-1,2-Propanediol is finding new applications in emerging fields like RNA interference (RNAi) therapeutics, where it's used in the synthesis of lipid-like delivery molecules. This versatility further elevates its importance. Procurement managers should also inquire about packaging options, with 250kg drums being a common standard, and recommended storage conditions (cool, dry, well-ventilated) to maintain product integrity.

Ultimately, securing a reliable supply of high-quality 3-Amino-1,2-Propanediol involves thorough due diligence. By focusing on purity, supplier credentials, and clear communication regarding your needs, you can ensure a successful procurement process. To learn more about sourcing this vital intermediate and to request a quote, consider engaging with experienced chemical manufacturers who specialize in pharmaceutical intermediates.