For professionals in the pharmaceutical and fine chemical industries, the reliable sourcing of key intermediates is paramount. One such critical compound is 3-Bromoisoquinoline, identified by its CAS number 34784-02-6. This heterocyclic organic compound serves as a vital building block in the synthesis of numerous Active Pharmaceutical Ingredients (APIs) and is indispensable for advanced organic chemistry research. This article aims to guide potential buyers on understanding its specifications and locating dependable manufacturers.

Understanding 3-Bromoisoquinoline (CAS 34784-02-6) Specifications

When procuring 3-Bromoisoquinoline, several key specifications need to be considered to ensure it meets your project's requirements. The most crucial aspects include:

  • Purity: For most pharmaceutical applications, a high purity level is essential. Typically, 3-Bromoisoquinoline is available with a minimum purity of 99.0%. This level of purity is critical for complex synthetic routes where even trace impurities can affect reaction yields and the quality of the final product.
  • Molecular Formula & Weight: The molecular formula is C9H6BrN, with a molecular weight of approximately 208.05 g/mol. Understanding these fundamental properties is key for stoichiometric calculations in synthesis.
  • Physical Appearance: It is commonly described as a white to light brown solid. While the color can vary slightly depending on the grade and manufacturer, it should be consistent with a solid form at room temperature.
  • Melting Point: The reported melting point is typically in the range of 63-64 °C. This physical property serves as a useful indicator of purity.
  • Boiling Point: The boiling point is around 316.3±15.0 °C (predicted), indicating its stability under certain thermal conditions.
  • Storage Conditions: To maintain its quality, 3-Bromoisoquinoline should be stored in a dark place, sealed, and kept dry at room temperature. Proper storage is vital for preserving its chemical integrity over time.

Key Applications in Pharmaceutical R&D and Beyond

The versatility of 3-Bromoisoquinoline stems from its reactive bromine atom and its isoquinoline core structure. It finds extensive use in:

  • API Synthesis: It acts as a crucial intermediate in the multi-step synthesis of various pharmaceutical drugs. Its functionalization allows for the introduction of diverse chemical moieties, enabling the creation of complex molecular architectures characteristic of many modern medicines. If you are looking to buy 3-Bromoisoquinoline for your API production, ensuring a consistent supply from a reliable manufacturer is paramount.
  • Organic Synthesis Research: Academic and industrial researchers frequently employ 3-Bromoisoquinoline in the development of novel synthetic methodologies, catalysis studies, and the exploration of new heterocyclic compounds. Its predictable reactivity makes it an excellent substrate for various coupling reactions, such as Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
  • Material Science: While less common, certain derivatives of isoquinoline are explored for their optoelectronic properties, making intermediates like 3-Bromoisoquinoline potentially valuable in the development of new materials.

Finding Reliable 3-Bromoisoquinoline Manufacturers and Suppliers in China

For procurement professionals and research scientists, identifying trustworthy sources for chemical raw materials is a critical task. China has emerged as a global hub for chemical manufacturing, offering a wide array of pharmaceutical intermediates at competitive prices. When searching for a 3-Bromoisoquinoline manufacturer or supplier, consider the following:

  • Purity Assurance: Always verify the stated purity and inquire about Certificates of Analysis (CoA) for batch consistency.
  • Production Capacity: For larger orders, ensure the manufacturer has the capacity to meet your volume requirements consistently.
  • Quality Certifications: Look for manufacturers adhering to international quality standards.
  • Customer Service and Support: A responsive supplier offering free samples for R&D evaluation and providing timely technical support can significantly streamline your procurement process. Many suppliers in China offer these services to build long-term partnerships.
  • Pricing and Delivery: Compare prices from multiple suppliers, but also consider the total cost of ownership, including shipping and potential import duties. Enquire about payment terms and estimated delivery times to your location. Purchasing directly from a China manufacturer often provides the best price for 3-Bromoisoquinoline.

Conclusion

3-Bromoisoquinoline (CAS 34784-02-6) is an indispensable intermediate for the pharmaceutical and chemical research sectors. By understanding its specifications and knowing where to find reputable manufacturers in China, buyers can secure a consistent and high-quality supply. When you need to buy this essential chemical, prioritizing purity, reliability, and competitive pricing will lead to successful project outcomes. We are dedicated to being your trusted partner in sourcing this critical compound.