For procurement managers and R&D scientists in the pharmaceutical and fine chemical sectors, securing a consistent supply of high-purity Methyl 3,4,5-trimethoxybenzoate (CAS: 1916-07-0) is paramount. This essential intermediate plays a critical role in the synthesis of several key therapeutic compounds, making its quality and availability direct determinants of project success. This article serves as a guide for buyers looking to purchase this vital chemical, focusing on identifying reliable manufacturers and suppliers, particularly within China.

Methyl 3,4,5-trimethoxybenzoate is characterized by its white crystalline powder appearance and a high purity level, typically exceeding 99.0%. Its molecular formula is C11H14O5, with a molecular weight of 226.23. The compound's physical properties, such as a melting point of 82-84°C and a boiling point of 274-275°C, indicate good stability under standard processing conditions. These characteristics are crucial for its use in sensitive pharmaceutical synthesis pathways.

The primary application driving demand for Methyl 3,4,5-trimethoxybenzoate is its function as a pharmaceutical intermediate. It is notably the main raw material for trimetozine, an anxiolytic medication, and is also integral to the production of trimebutine maleate, a drug used to manage gastrointestinal disorders. Its structural features also lend themselves to broader organic synthesis applications, making it a versatile building block for chemical researchers.

When considering where to buy Methyl 3,4,5-trimethoxybenzoate, buyers often look for manufacturers and suppliers who can guarantee both quality and competitive pricing. China has emerged as a significant hub for the production of fine chemicals and pharmaceutical intermediates, offering access to a broad range of suppliers. However, the key challenge lies in identifying those with robust quality control systems and a proven track record.

For procurement specialists, understanding the typical price of Methyl 3,4,5-trimethoxybenzoate involves evaluating purity, quantity, and supplier reliability. Engaging with established Methyl 3,4,5-trimethoxybenzoate manufacturers in China directly can often yield more favorable terms and direct access to technical support. Furthermore, companies seeking a dependable CAS 1916-07-0 supplier should prioritize those who offer comprehensive product specifications, certificates of analysis (CoA), and adherence to international quality standards.

The synthesis of Methyl 3,4,5-trimethoxybenzoate typically involves the esterification of 3,4,5-trimethoxybenzoic acid with methanol, a process that, when optimized, yields the high purity required by the pharmaceutical industry. Buyers interested in the synthesis of trimetozine or the production of trimebutine maleate intermediates will find that sourcing this compound from reputable manufacturers is the first step towards ensuring the efficacy and safety of their final pharmaceutical products.

In conclusion, for any organization looking to procure Methyl 3,4,5-trimethoxybenzoate, a strategic approach to supplier selection is essential. Prioritizing manufacturers with a strong commitment to quality, competitive pricing, and consistent supply, especially those based in China, will pave the way for successful drug development and manufacturing initiatives.