For pharmaceutical manufacturers and R&D scientists, sourcing critical intermediates like 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride (CAS 70918-74-0) is a cornerstone of successful drug development and production. As a leading manufacturer and supplier in China, we understand the stringent quality requirements and the importance of a reliable supply chain for such compounds. This article delves into the key considerations when looking to buy this essential pharmaceutical intermediate.

Understanding the Importance of Purity and Specifications

1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride is primarily recognized for its role as a key intermediate in the synthesis of Doxazosin. Doxazosin is a well-established alpha-1 adrenoceptor antagonist used to treat conditions like hypertension and benign prostatic hyperplasia. The efficacy and safety of the final pharmaceutical product are directly dependent on the quality of its intermediates. Therefore, ensuring a high purity level, typically above 98%, is paramount. Manufacturers must provide detailed specifications, including appearance, solubility, and stability, along with rigorous quality control measures.

What to Look for in a Supplier

When seeking to purchase 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride, it is crucial to partner with a reputable manufacturer or supplier. Key indicators of reliability include:

  • Manufacturing Expertise: A supplier with in-house manufacturing capabilities in China offers greater control over quality and production consistency.
  • Regulatory Compliance: Look for suppliers who can provide necessary documentation such as Certificates of Analysis (CoA), Material Safety Data Sheets (MSDS), and potentially support for DMF or other regulatory filings.
  • Scalability and Availability: Ensure the supplier can meet both your R&D scale requirements and your commercial bulk purchase needs with consistent availability.
  • Competitive Pricing: While quality is paramount, securing a competitive price from your supplier is essential for cost-effectiveness in drug manufacturing.
  • Customer Support and Responsiveness: A responsive supplier who can answer technical questions and provide timely updates on orders is invaluable.

The Role of a Chinese Manufacturer

China has emerged as a significant hub for pharmaceutical intermediate production, offering a robust ecosystem of manufacturers with advanced synthesis capabilities. By choosing a Chinese manufacturer for your 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride needs, you can benefit from competitive pricing and access to specialized expertise. However, due diligence in vetting suppliers is essential to guarantee product quality and supply chain integrity.

In Conclusion

Securing a dependable source for high-quality 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride is critical for the success of your pharmaceutical projects. Prioritize purity, regulatory support, and supplier reliability. As a dedicated supplier of pharmaceutical intermediates, we are committed to meeting these standards and supporting your procurement needs. Contact us today to get a quote or inquire about purchasing this vital intermediate.