As a leading manufacturer and supplier in the chemical industry, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality pharmaceutical intermediates that drive innovation. N-Boc-piperidine-3-methanol (CAS 116574-71-1) is one such compound, playing a pivotal role in the synthesis of a wide array of therapeutic agents. This article offers an in-depth look at this compound from a manufacturer's perspective, covering its essential properties, diverse applications, and the importance of strategic sourcing for R&D and production.

N-Boc-piperidine-3-methanol is a key intermediate characterized by its piperidine ring structure, which is a common motif in many pharmacologically active molecules. The tert-butoxycarbonyl (Boc) group serves as a protective layer for the nitrogen atom, enabling selective reactions and facilitating purification processes. The presence of the hydroxymethyl group at the 3-position offers a reactive site for various synthetic transformations, making this compound exceptionally versatile. It is typically supplied as a white crystalline powder, with a melting point of 77-81 °C, and demonstrates good solubility in organic solvents like methanol and DMF, which are frequently used in synthetic chemistry.

The utility of N-Boc-piperidine-3-methanol is most prominently seen in its application as a building block for complex organic molecules within the pharmaceutical sector. It is an indispensable intermediate in the synthesis of compounds designed to treat a broad spectrum of diseases. Notably, it is utilized in the development of Pim-1 inhibitors, which are critical in cancer research, and various receptor antagonists, such as Vasopressin1b receptor antagonists and CXCR4 antagonists, which are explored for their potential in managing conditions ranging from cardiovascular issues to HIV infection. The consistent demand for this intermediate underscores its importance in advancing drug discovery and development.

From a manufacturer's standpoint, ensuring the quality and purity of N-Boc-piperidine-3-methanol is paramount. We employ rigorous quality control measures throughout our production process to guarantee that each batch meets stringent purity specifications, often exceeding 97%. This commitment to quality ensures that our clients can rely on the consistency and performance of the intermediate in their sensitive synthetic procedures. We provide comprehensive documentation, including detailed Certificates of Analysis (COA), to support our customers’ research and regulatory needs.

For pharmaceutical companies and research institutions, sourcing N-Boc-piperidine-3-methanol requires careful consideration of supplier reliability and cost-effectiveness. As a direct manufacturer, we offer a stable supply chain and competitive pricing, making it easier for our clients to buy the quantities they need for both laboratory-scale research and commercial production. We understand that timely delivery and consistent availability are crucial for project success, and our logistics are optimized to meet these demands.

In essence, N-Boc-piperidine-3-methanol is more than just a chemical compound; it is a vital enabler of pharmaceutical innovation. By partnering with experienced manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., you can ensure access to a high-quality intermediate that supports efficient synthesis and accelerates the journey from discovery to market. We invite you to explore our product offerings and connect with our team to discuss your requirements and secure your supply of N-Boc-piperidine-3-methanol.