For professionals in the pharmaceutical and chemical research sectors, understanding the properties and applications of key intermediates is crucial for successful project execution. N-Boc-piperidine-3-methanol, identified by CAS number 116574-71-1, is a significant heterocyclic compound widely used in organic synthesis. This article provides an overview of its chemical characteristics, diverse applications, and practical advice for sourcing this vital intermediate from reliable manufacturers.

N-Boc-piperidine-3-methanol is characterized by its piperidine ring, functionalized with a hydroxymethyl group at the 3-position and protected by a tert-butoxycarbonyl (Boc) group on the nitrogen atom. This Boc protection is a standard practice in organic synthesis, as it renders the amine less reactive and more stable, allowing for selective chemical transformations at other sites. The hydroxymethyl group, on the other hand, provides a reactive hydroxyl functionality that can be easily modified through esterification, etherification, or oxidation reactions. This dual functionality makes it a highly versatile building block. Physically, it typically appears as a white crystalline powder, with a melting point in the range of 77-81 °C, and exhibits good solubility in common organic solvents like methanol and dimethylformamide (DMF), which are frequently used in synthesis.

The applications of N-Boc-piperidine-3-methanol are predominantly within the realm of pharmaceutical research and development. It serves as a key intermediate in the synthesis of a variety of drug candidates and bioactive molecules. Its utility is particularly noted in the creation of compounds such as Pim-1 inhibitors, which are explored for their anti-cancer properties. It also features in the synthesis pathways for Vasopressin1b receptor antagonists and CXCR4 antagonists, compounds being investigated for their roles in treating conditions like cardiovascular diseases and as potential anti-HIV agents. The consistent demand for these therapeutic areas drives the need for reliable access to this intermediate.

When considering the purchase of N-Boc-piperidine-3-methanol for R&D purposes, it is imperative to source from reputable manufacturers and suppliers. As a B2B chemical supplier, NINGBO INNO PHARMCHEM CO.,LTD. prioritizes product purity and quality. We ensure that our N-Boc-piperidine-3-methanol meets high industry standards, typically exceeding 97% purity, and provide comprehensive Certificates of Analysis (COA) with each order. This documentation is essential for validating the intermediate's quality and suitability for your specific research needs.

Furthermore, establishing a reliable supply chain is critical for the continuity of research projects. We are committed to providing consistent availability and competitive pricing for N-Boc-piperidine-3-methanol, catering to both small-scale research needs and larger-volume requirements. We encourage potential customers to request a quote from our sales team to explore bulk purchasing options and discuss how we can meet your specific sourcing requirements.

In summary, N-Boc-piperidine-3-methanol is a fundamental intermediate in modern pharmaceutical synthesis, enabling the development of novel therapeutics. Understanding its chemical properties and applications, and ensuring procurement from trusted sources like NINGBO INNO PHARMCHEM CO.,LTD., is key to the success of your R&D endeavors. We are here to support your scientific journey with high-quality chemicals and reliable service.