In the complex world of pharmaceutical manufacturing, the sourcing of high-quality intermediates is paramount to the success of drug development and production. Among these crucial compounds, 1,2,4-Thiadiazole-3-acetic acid, 5-amino-a-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, (Z)-, identified by its CAS number 76028-96-1, stands out as a significant building block. Its unique chemical structure makes it indispensable in the synthesis of advanced therapeutic agents, most notably ceftolozane, a potent antibiotic.

For procurement managers and research scientists, understanding the properties and sourcing channels for such vital materials is key. This article aims to guide you through the essential considerations when looking to buy this specific thiadiazole derivative. We will delve into why its purity and availability are critical, and what to look for in a trusted manufacturer and supplier.

Understanding the Significance of CAS 76028-96-1

The molecule, often referred to by its CAS number 76028-96-1, is a complex organic compound that plays a pivotal role as an intermediate in the multi-step synthesis of ceftolozane. Ceftolozane, a fifth-generation cephalosporin antibiotic, is vital in combating serious infections caused by multi-drug resistant Gram-negative bacteria. The precision required in synthesizing such drugs means that the intermediate’s quality, particularly its purity and isomeric form, directly impacts the final API’s efficacy and safety profile.

Key Considerations When Purchasing: Purity and Specifications

When you intend to purchase this pharmaceutical intermediate, always prioritize suppliers who can provide detailed Certificates of Analysis (CoA). For CAS 76028-96-1, typical specifications include a high purity level, often exceeding 97%, and confirmation of the correct isomeric form (Z-isomer). A reputable manufacturer will ensure lot-to-lot consistency, which is critical for scaling up production and maintaining regulatory compliance.

Finding a Reliable Manufacturer and Supplier

Identifying a dependable source is crucial for ensuring a stable supply chain. Look for manufacturers and suppliers with established track records in fine chemical production and a strong understanding of pharmaceutical industry requirements. When you search for a “1,2,4-Thiadiazole-3-acetic acid derivative manufacturer” or “CAS 76028-96-1 supplier,” consider these factors:

  • Manufacturing Capabilities: Does the supplier have robust production facilities and quality control systems in place?
  • Technical Support: Can they provide expert advice on handling and application?
  • Global Reach: Do they offer international shipping and adhere to import/export regulations?
  • Competitive Pricing: While quality is paramount, securing a fair price is essential for cost-effectiveness. Obtaining quotes from several suppliers can be beneficial.

Many leading chemical manufacturers are based in China, offering competitive pricing and significant production capacities. A diligent search for “buy 5-amino-a-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-1,2,4-thiadiazole-3-acetic acid” or “Z-isomer pharmaceutical intermediate price” will reveal several reputable options.

The Importance of a Strategic Partnership

Establishing a strong relationship with your chemical supplier goes beyond a single transaction. For critical intermediates like CAS 76028-96-1, a strategic partnership ensures consistent quality, reliable delivery, and potential for future collaboration. As a leading manufacturer and supplier of fine chemicals, we are committed to meeting the rigorous demands of the pharmaceutical industry. We invite you to contact us for detailed specifications, pricing, and to request a sample of our high-purity 1,2,4-Thiadiazole-3-acetic acid derivative. Secure your essential raw materials today and advance your pharmaceutical innovations.