In the complex landscape of pharmaceutical manufacturing and chemical synthesis, sourcing high-quality intermediates is paramount. Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate, identified by its CAS number 1458-01-1, stands out as a critical building block, particularly for the production of the widely used diuretic, Amiloride. For procurement managers and R&D scientists, understanding the nuances of this compound and its supply chain is essential for ensuring project success and cost-effectiveness.

This heterocyclic compound, often referred to as Amiloride Related Compound A, is characterized by its pyrazine ring structure with specific amino and chlorine substituents. Its primary utility lies in its role as a precursor in synthesizing more complex pharmaceutical molecules. The demand for Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate is directly linked to the global pharmaceutical market, especially for cardiovascular and diuretic medications. Therefore, securing a consistent and high-purity supply is a strategic imperative for many companies.

When looking to buy Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate, several factors come into play. Purity is often the most critical specification, typically requiring >95% or even higher for pharmaceutical applications to avoid introducing unwanted impurities into the final drug product. Manufacturers in China have become significant global suppliers, offering competitive pricing due to economies of scale and advanced synthesis capabilities. For instance, finding a reliable methyl 3,5-diamino-6-chloropyrazine-2-carboxylate manufacturer China can significantly reduce procurement costs.

The CAS 1458-01-1 price can vary depending on the supplier, quantity, and purity level. Bulk purchases usually command lower per-unit prices. It is advisable to solicit quotes from multiple verified suppliers. Engaging with a reputable pharmaceutical intermediate supplier is crucial. These suppliers not only provide the chemical but also offer technical documentation such as Certificates of Analysis (CoA), Safety Data Sheets (SDS), and sometimes even support for regulatory filings.

For those specifically interested in its role as an impurity or reference standard, sourcing Amiloride Related Compound A for sale is essential for quality control processes. Ensuring that the supplier can provide this with the required certification is key.

The synthesis of Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate itself involves multi-step organic chemistry, and manufacturers often invest heavily in optimizing these processes for yield and purity. Understanding these synthesis routes can provide insights into potential supply chain risks and quality control measures.

In conclusion, sourcing Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate requires a strategic approach. By focusing on purity, supplier reliability, competitive pricing, and understanding its key applications, procurement managers can secure this vital chemical intermediate efficiently. Engaging with experienced manufacturers and suppliers, particularly those based in China, is a common and effective strategy for obtaining this essential compound.