In the dynamic landscape of chemical synthesis and pharmaceutical development, certain intermediates emerge as cornerstones for innovation. (R)-1-Benzylpiperidin-3-ol (CAS 91599-81-4) is one such compound, valued for its specific chiral properties and utility as a building block. This article provides a focused overview of this important chemical, including its key characteristics, applications, and insights into sourcing it effectively, particularly from manufacturers in China.

(R)-1-Benzylpiperidin-3-ol is a chiral piperidine derivative characterized by its chemical formula C12H17NO and a molecular weight of approximately 191.27 g/mol. Typically supplied as a liquid, its physical properties include a boiling point of around 275°C and a density of 1.07 g/mL at 25°C. Its optical activity, often specified as [α]24/D 12° in methanol, is a critical parameter for its use in stereoselective synthesis. These detailed specifications are vital for researchers and manufacturers when evaluating product quality and suitability for specific processes.

The primary utility of (R)-1-Benzylpiperidin-3-ol lies in its role as a pharmaceutical intermediate. It is instrumental in the synthesis of complex APIs, where its specific enantiomeric form is crucial for the final drug's efficacy and safety. A notable application involves its use in preparing in vivo probes for accurately measuring endogenous acetylcholine levels, a key area in neuroscience research. Its benzylpiperidine scaffold also lends itself to the development of compounds with potential hypotensive or other pharmacological activities.

For procurement professionals and research scientists looking to buy (R)-1-Benzylpiperidin-3-ol, understanding the global supply chain is essential. China has become a leading source for many fine chemicals and intermediates, including this one. Many Chinese manufacturers offer competitive pricing and robust production capabilities, making them attractive partners. When sourcing from China, it is advisable to look for suppliers with a proven track record, clear quality control procedures, and the ability to provide comprehensive Certificates of Analysis (COA).

When engaging with potential suppliers, inquire about their minimum order quantities (MOQs) and packaging options. Whether you require small research quantities or larger industrial volumes, a reliable manufacturer should be able to accommodate your needs. Furthermore, clear communication regarding delivery timelines and adherence to safety standards during shipping is crucial for a smooth procurement process.

In summary, (R)-1-Benzylpiperidin-3-ol is a valuable asset in the pharmaceutical and chemical research sectors. Its unique properties and applications, especially as a chiral building block, make it indispensable for advancing drug discovery and scientific understanding. By diligently researching and vetting manufacturers, particularly those based in China, you can secure a consistent and high-quality supply of this critical chemical intermediate to support your ongoing projects.