In the realm of advanced chemical synthesis, particularly within the pharmaceutical and fine chemical sectors, the selection of appropriate intermediates is crucial for efficient and successful outcomes. 1-Iodonaphthalene (CAS: 90-14-2) emerges as a key player due to its specific chemical properties and versatility. Understanding its applications, market availability, and optimal sourcing strategies, including partnerships with China-based manufacturers, is vital for industry professionals.

1-Iodonaphthalene: A Versatile Synthetic Tool

1-Iodonaphthalene is a naphthalene derivative characterized by an iodine atom substituted at the alpha (1) position. This molecular configuration makes it a highly reactive compound, especially in carbon-carbon bond-forming reactions. Its typical form is a light yellow liquid, with an impressive boiling point of 302°C at 760 mmHg. Crucially for pharmaceutical applications, it is often supplied at a minimum purity of 97%. This high degree of purity ensures that it can be effectively integrated into complex synthetic pathways without introducing detrimental impurities, which is critical for developing Active Pharmaceutical Ingredients (APIs) and other high-value chemicals.

The reactivity of the iodine atom in 1-iodonaphthalene allows it to participate in a variety of palladium-catalyzed cross-coupling reactions. These reactions are foundational in modern organic chemistry, enabling chemists to efficiently construct intricate molecular architectures. The applications are diverse:

  • Drug Discovery and Synthesis: It serves as a vital intermediate in the creation of novel pharmaceutical compounds and the optimization of synthetic routes for existing drugs.
  • Material Science: Its structure can be incorporated into advanced materials, leveraging the properties of the naphthalene core and the potential for further functionalization.
  • Agrochemicals: In some instances, it can be utilized in the synthesis of crop protection agents.
  • Research and Academia: It is a common reagent in academic labs for exploring new reactions and synthesizing novel organic molecules.

Sourcing Strategies: Price, Quality, and China's Role

For companies looking to buy 1-iodonaphthalene, the global market offers various options. However, China has become a dominant force in the production of chemical intermediates, providing a robust and cost-effective supply chain. When searching for a reliable 1-iodonaphthalene supplier in China, it is essential to prioritize quality and consistency. Factors to consider include the supplier's ability to consistently meet purity specifications (e.g., 97% minimum), competitive CAS 90-14-2 price points, and a proven track record of reliable delivery. Obtaining quotes from multiple manufacturers and verifying their technical documentation, such as Certificates of Analysis, is a standard practice.

Ningbo Inno Pharmchem is a leading 1-iodonaphthalene manufacturer committed to providing the global market with high-quality chemical intermediates. Our focus on stringent quality control, advanced manufacturing processes, and responsive customer service ensures that we meet the demanding requirements of the pharmaceutical and chemical industries. We invite you to partner with us for your 1-iodonaphthalene sourcing needs, benefiting from our competitive pricing and unwavering commitment to product excellence.