The intricate process of drug development and manufacturing relies on a robust global supply chain for essential chemical intermediates. Among these, 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one (CAS 55314-16-4) holds a position of considerable importance. Its role as a direct precursor to Imatinib and Nilotinib, two critical tyrosine kinase inhibitors used in cancer treatment, underscores its significance.

The synthesis of 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one typically involves organic reactions that require precise control over conditions and reactants. One common synthetic route involves the reaction of 3-acetylpyridine with N,N-dimethylformamide dimethyl acetal, often catalyzed by a small amount of acetic acid. This process yields the desired intermediate, which is then purified to meet stringent pharmaceutical standards, often exceeding 98.0% purity. The physical characteristics, such as its light yellow powder form and a melting point of 86-88°C, are important quality markers for the final product.

The global supply chain for this intermediate is multifaceted. Major manufacturing hubs, particularly in China, play a crucial role in meeting the worldwide demand. Pharmaceutical companies and contract manufacturers worldwide seek to buy CAS 55314-16-4 from reliable sources that can guarantee consistent quality and scalability. As a dedicated manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. focuses on optimizing these synthetic pathways and ensuring robust quality control measures are in place. This dedication allows us to provide a dependable supply of this critical intermediate at competitive prices.

Challenges in the supply chain can arise from geopolitical factors, raw material availability, and stringent regulatory requirements. However, by partnering with experienced chemical manufacturers who prioritize transparency and quality, these challenges can be effectively managed. For businesses looking to secure their supply of 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, understanding the synthesis process and the supplier's capabilities is key. We invite you to request a quote to explore how we can meet your bulk purchasing needs and contribute to your production success.