In the relentless pursuit of effective cancer treatments, the precise synthesis of Active Pharmaceutical Ingredients (APIs) is paramount. Among the critical building blocks enabling these life-saving drugs is 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one (CAS 55314-16-4). This compound, often referred to by its synonyms such as 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one, plays a pivotal role as an intermediate in the production of globally recognized targeted therapies.

The pharmaceutical industry relies heavily on a consistent and high-quality supply of such intermediates. 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one is specifically recognized for its importance in the synthesis pathways of two major tyrosine kinase inhibitors (TKIs): Imatinib and Nilotinib. Imatinib, marketed under brand names like Gleevec, revolutionized the treatment of chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). Nilotinib, another powerful TKI, offers an alternative and often more effective treatment for CML, particularly in cases resistant to Imatinib.

The chemical structure of 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, with its molecular formula C10H12N2O and a molecular weight of 176.21, is carefully engineered to integrate seamlessly into complex synthetic routes. Its physical characteristics, typically a light yellow powder with a melting point around 86-88°C, are indicative of its purity and suitability for pharmaceutical applications. The ability to reliably buy this intermediate from a trusted manufacturer is crucial for pharmaceutical companies and contract research organizations (CROs) involved in drug development and production.

Sourcing from a reputable supplier in China, for instance, can offer significant advantages in terms of both cost-effectiveness and scalability. When looking to purchase this essential compound, it's vital to ensure it meets stringent purity standards (often ≥98.0%) to guarantee the efficacy and safety of the final drug product. Companies that specialize in producing these intermediates, like NINGBO INNO PHARMCHEM CO.,LTD., are essential partners in the global pharmaceutical supply chain. They ensure that researchers and manufacturers have access to the necessary materials to continue developing and producing vital medications.

The demand for high-quality pharmaceutical intermediates is continuous, driven by the ongoing need for effective treatments for diseases like cancer. By understanding the critical role of compounds like 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one, the industry can continue to innovate and bring forward new therapeutic options. For those seeking to secure a reliable supply, exploring options from established chemical manufacturers that can provide detailed specifications, certificates of analysis, and competitive pricing is the first step towards successful pharmaceutical production.