Organic chemistry is a field driven by the creation and manipulation of molecules, where chiral building blocks play an increasingly vital role. (S)-1-Cbz-3-pyrrolidinol (CAS: 100858-32-0) is one such compound, valued for its specific stereochemistry and its utility in complex synthesis. For researchers in both academic institutions and industrial labs, understanding its synthesis pathways and diverse applications is key to leveraging its potential in new chemical discoveries.

Understanding the Chemistry of (S)-1-Cbz-3-pyrrolidinol

(S)-1-Cbz-3-pyrrolidinol, with its molecular formula C12H15NO3 and a molecular weight of 221.25, presents a chiral center at the 3-position of the pyrrolidine ring. The presence of the benzyloxycarbonyl (Cbz) group serves as a protecting group, which can be selectively removed later in synthesis. Its physical form is typically a white to off-white solid, with a melting point range between 71-77 °C. The synthesis often involves enzymatic or chemical reduction of related pyrrolidone derivatives, ensuring the desired enantiomeric purity is maintained. Academic and industrial chemists often seek to buy (S)-1-Cbz-3-pyrrolidinol from specialized suppliers to ensure high purity (u2265 95%) and consistent quality for their experiments.

Diverse Applications in Organic Synthesis

The applications of (S)-1-Cbz-3-pyrrolidinol are widespread within organic chemistry. It serves as a fundamental building block for synthesizing a variety of complex organic molecules, including:

  • Pharmaceutical Intermediates: It's a key precursor for creating enantiomerically pure APIs, essential for drugs targeting conditions like neurological disorders.
  • Peptidomimetics: Its structure can be incorporated into molecules that mimic peptides, offering enhanced stability and bioavailability.
  • Catalyst Development: Researchers may utilize it in the design of novel chiral catalysts for asymmetric transformations.
  • Material Science: Its properties can be explored in the development of functional materials with specific structural attributes.

Sourcing and Considerations for Researchers

When undertaking research that requires (S)-1-Cbz-3-pyrrolidinol, it is important for chemists to partner with reliable manufacturers. Factors such as the availability of different grades, clear specifications, and responsive customer service are crucial. Understanding the price structure and lead times when you purchase this compound can aid in project planning. Many dedicated chemical companies provide detailed product information, including safety data sheets (SDS) and technical data sheets (TDS), which are invaluable resources for experimental design and safe handling.

By securing a consistent supply of high-quality (S)-1-Cbz-3-pyrrolidinol, organic chemists can push the boundaries of molecular design and contribute to advancements across various scientific disciplines.