The pharmaceutical industry relies heavily on specialized chemical intermediates to build complex Active Pharmaceutical Ingredients (APIs). 1-Bromo-3,5-Dimethoxybenzene (CAS 20469-65-2) is a prime example, serving as a versatile building block in numerous synthetic routes. This article examines its synthesis, utility in API development, and considerations for procurement.

1-Bromo-3,5-Dimethoxybenzene, with CAS number 20469-65-2, is characterized by its molecular formula C8H9BrO2 and its typical crystalline form. Manufacturers often emphasize its high purity, usually ≥ 98.0% by GC, which is essential for its intended use. While direct synthesis methods are typically proprietary to manufacturers, common pathways might involve the functionalization of dimethoxybenzene derivatives. The availability of this compound from various manufacturers signifies its importance in the chemical supply chain.

The primary utility of 1-Bromo-3,5-Dimethoxybenzene in API development is its role as a reactant in cross-coupling reactions. These reactions are fundamental in organic chemistry for forming carbon-carbon bonds, enabling the construction of intricate molecular frameworks characteristic of many modern drugs. Researchers and process chemists select this intermediate for its specific reactivity and the structural motif it introduces, which can be critical for the biological activity of the final API.

For R&D scientists and procurement managers, understanding the market landscape for this intermediate is crucial. When you need to buy 1-Bromo-3,5-Dimethoxybenzene, sourcing from established manufacturers guarantees product quality and consistency. Comparative price inquiries are standard practice to secure the best value, especially for larger quantities required in later stages of drug development. A robust supply chain is vital, and partnering with responsive suppliers ensures that your research timelines are met.

In summary, 1-Bromo-3,5-Dimethoxybenzene (CAS 20469-65-2) is a cornerstone intermediate for API development, valued for its purity and synthetic versatility. Manufacturers providing this compound contribute significantly to the pharmaceutical research ecosystem. By focusing on quality and reliable supply from experienced providers, companies can effectively leverage this chemical for their drug discovery and manufacturing needs.