Innovation in chemistry often hinges on the availability of specialized building blocks that enable the construction of complex molecular architectures. Tert-butyl 4,7-diazaspiro[2.5]octane-4-carboxylate is one such molecule, offering unique spirocyclic features that are highly prized in pharmaceutical research and fine chemical synthesis. This article aims to provide chemists and procurement specialists with insight into its properties, applications, and how to efficiently source this critical intermediate.

The Unique Structure and Properties

Tert-butyl 4,7-diazaspiro[2.5]octane-4-carboxylate (CAS: 674792-08-6) is distinguished by its spirocyclic structure, a feature that imparts significant conformational rigidity. This characteristic is often beneficial in drug design, potentially leading to improved binding affinity and selectivity for biological targets. The molecule's composition includes a protected diamine within the spirocyclic framework, making it a versatile synthon. Typically supplied as an off-white to light yellow solid with high purity (often exceeding 97%), it is an ideal reagent for demanding synthetic transformations. Its molecular formula is C11H20N2O2, and it has a molecular weight of 212.29.

Applications in Pharmaceutical and Chemical Synthesis

The primary application domain for tert-butyl 4,7-diazaspiro[2.5]octane-4-carboxylate is in the synthesis of active pharmaceutical ingredients (APIs). Medicinal chemists utilize this intermediate to introduce novel spirocyclic motifs into drug candidates, exploring new chemical space and potentially enhancing therapeutic properties. Beyond pharmaceuticals, its utility extends to various areas of fine chemical synthesis where constrained amine structures are beneficial. Researchers looking to buy this compound for their projects are often seeking to build complex heterocyclic systems or create molecular libraries for screening.

Sourcing Strategies and Supplier Selection

For chemical innovators and procurement professionals, identifying a reliable supplier of tert-butyl 4,7-diazaspiro[2.5]octane-4-carboxylate is paramount. When considering sourcing from China, it is essential to partner with established manufacturers that prioritize quality and consistency. Key considerations include:

  • Purity Verification: Always request a Certificate of Analysis (CoA) to confirm purity and assay.
  • Batch Consistency: Ensure the supplier can guarantee uniformity across different production batches.
  • Pricing and Quotes: Obtain detailed quotes to understand the price for your required quantities.
  • Technical Support: A responsive supplier can offer valuable insights into product handling and applications.

Choosing a reputable Chinese manufacturer ensures access to high-quality intermediates at competitive prices. We are a dedicated supplier of such specialized chemicals, committed to supporting your innovation. To purchase tert-butyl 4,7-diazaspiro[2.5]octane-4-carboxylate and advance your chemical endeavors, contact us for a quote today.