The Chemistry Behind 2-Amino-5-bromo-3-nitropyridine: Synthesis and Applications
2-Amino-5-bromo-3-nitropyridine (CAS 6945-68-2) is a fascinating organic compound that serves as a critical building block in numerous chemical synthesis processes. Its molecular structure, C5H4BrN3O2, with a molecular weight of 218.01, features a pyridine core substituted with an amino group, a bromine atom, and a nitro group. This specific arrangement of functional groups imbues the molecule with unique reactivity, making it highly sought after in fields ranging from pharmaceuticals to advanced materials.
The synthesis of 2-Amino-5-bromo-3-nitropyridine is typically achieved through the electrophilic nitration of 2-amino-5-bromopyridine. This reaction often involves using a nitrating mixture, such as concentrated sulfuric acid and nitric acid, under controlled low temperatures (0-5°C) to ensure regioselectivity and prevent unwanted side reactions. The process requires careful monitoring to achieve high yields and purity, often followed by neutralization and isolation of the precipitate. Understanding the nuances of its CAS 6945-68-2 synthesis is key for any manufacturer aiming for quality production.
The primary applications of 2-Amino-5-bromo-3-nitropyridine are as a key intermediate in the synthesis of more complex molecules. It is extensively used in the preparation of azaquinoxalinedione, a compound with reported applications in various chemical research areas. Furthermore, it plays a vital role in the synthesis of 2,3-diaminopyridine, another important intermediate for pharmaceuticals and specialty chemicals. The ability to reliably buy 2-amino-5-bromo-3-nitropyridine with a high assay (>98%) directly impacts the success of these downstream syntheses.
The physical properties of 2-Amino-5-bromo-3-nitropyridine, such as its appearance as a yellow to light-brown powder and a melting point of 205-208°C, are important identifiers for quality control. Its stability under recommended storage conditions (cool, ventilated place) also contributes to its practicality in laboratory and industrial settings. When sourcing this chemical, buyers often look for manufacturers that can provide not only the material but also comprehensive technical support regarding its handling and use.
For researchers and industrial chemists, having access to a dependable 2-amino-5-bromo-3-nitropyridine supplier is essential. Whether you are a small research lab or a large manufacturing facility, the consistent availability of high-quality intermediates like this one is fundamental to maintaining production schedules and driving innovation. Exploring the market for the best 2-amino-5-bromo-3-nitropyridine price while prioritizing purity and supplier reputation ensures a successful procurement strategy.
In conclusion, the chemistry of 2-Amino-5-bromo-3-nitropyridine is rich with potential. Its role as a versatile intermediate underscores its importance in modern organic synthesis. By understanding its synthesis, properties, and applications, and by partnering with reliable suppliers, researchers and manufacturers can effectively leverage this compound for groundbreaking advancements in various scientific and industrial fields.
Perspectives & Insights
Future Origin 2025
“In conclusion, the chemistry of 2-Amino-5-bromo-3-nitropyridine is rich with potential.”
Core Analyst 01
“Its role as a versatile intermediate underscores its importance in modern organic synthesis.”
Silicon Seeker One
“By understanding its synthesis, properties, and applications, and by partnering with reliable suppliers, researchers and manufacturers can effectively leverage this compound for groundbreaking advancements in various scientific and industrial fields.”