In the intricate world of chemical synthesis, certain molecules stand out for their versatility and potential to unlock new avenues of innovation. 3-Chloro-5-(trifluoromethyl)pyridin-2-amine (CAS No. 79456-26-1) is one such compound, a key intermediate that finds extensive use in the pharmaceutical and agrochemical industries, as well as in broader organic synthesis research. Its unique chemical structure, featuring a trifluoromethyl group and reactive functional groups on a pyridine ring, makes it a cornerstone for building complex molecular architectures.

Chemical Profile and Properties

3-Chloro-5-(trifluoromethyl)pyridin-2-amine is typically presented as a white to light yellow crystalline powder. Its molecular formula is C6H4ClF3N2, with a molecular weight of approximately 196.56 g/mol. The presence of the trifluoromethyl (-CF3) group is a critical feature. This highly electronegative group significantly influences the electronic distribution within the molecule, often leading to enhanced lipophilicity, increased metabolic stability, and altered reactivity – all desirable traits in drug design and the development of advanced agrochemicals. The chlorine atom and the amino group also serve as vital reactive handles for further chemical modifications, allowing chemists to construct a diverse range of derivatives.

Key physical properties such as melting point (often in the range of 84-94 °C) and boiling point provide important information for handling and reaction planning. For sourcing managers and researchers, ensuring a high purity level, typically 98% or greater, is essential for reproducible and successful synthetic outcomes.

Applications Driving Demand

The broad utility of 3-Chloro-5-(trifluoromethyl)pyridin-2-amine drives its demand across multiple sectors:

  • Pharmaceutical Research: It is employed as a building block for synthesizing potential drug candidates, where the trifluoromethyl moiety can improve pharmacokinetic properties.
  • Agrochemical Manufacturing: It serves as a key intermediate in the production of effective pesticides, herbicides, and fungicides, contributing to improved crop yields and protection.
  • Specialty Chemicals: Its unique structure makes it valuable in the synthesis of specialty chemicals and materials with tailored properties.
  • Academic and Industrial R&D: Researchers utilize it for exploring new chemical transformations and developing novel compounds.

For those looking to buy this essential intermediate, understanding its role and reliable sourcing options is crucial.

Sourcing Excellence: Partnering for Success

As a dedicated manufacturer and supplier of high-quality chemical intermediates, we offer 3-Chloro-5-(trifluoromethyl)pyridin-2-amine. We pride ourselves on providing products that meet stringent purity standards and ensuring a consistent supply chain. We understand the critical role this compound plays in your innovation pipeline. We encourage researchers and procurement specialists to contact us to discuss bulk purchasing, custom synthesis needs, and competitive pricing for this vital chemical building block. Let us be your trusted partner in chemical innovation.