In the complex world of pharmaceutical manufacturing, the quality of intermediate compounds directly dictates the efficacy and safety of the final drug product. One such critical intermediate is 4-(4-Chlorophenyl)piperidin-4-ol, identified by its CAS number 39512-49-7. This compound plays an indispensable role in the synthesis of Loperamide hydrochloride, a widely recognized and highly effective anti-diarrheal medication. Understanding the properties and reliable sourcing of this intermediate is paramount for pharmaceutical companies aiming for consistent quality and efficient production.

4-(4-Chlorophenyl)piperidin-4-ol, often appearing as a white to yellow crystalline powder, is characterized by its specific molecular formula, C11H14ClNO, and a molecular weight of approximately 211.69 g/mol. Its physical properties, such as a melting point typically between 137-140°C, indicate a stable compound suitable for various chemical processes. The stringent quality standards for this intermediate often require an assay of purity greater than or equal to 98.0%. This high level of purity is not merely a specification; it is a foundational requirement for ensuring that the downstream synthesis of Loperamide hydrochloride proceeds without introducing unwanted impurities that could compromise the drug's pharmacological profile.

The significance of 4-(4-Chlorophenyl)piperidin-4-ol lies in its structural contribution to Loperamide. As a key intermediate, it provides the necessary chemical framework that, through subsequent reactions, forms the active molecule responsible for slowing intestinal motility. The reliability of the supply chain for such intermediates is a critical consideration for manufacturers. Partnering with reputable pharmaceutical intermediate suppliers in China, known for their robust quality control systems and manufacturing capabilities, is a strategic choice. These suppliers are often equipped to handle the complexities of organic synthesis and ensure that the material meets international pharmaceutical standards, including rigorous purity requirements.

For companies involved in the production of Loperamide hydrochloride, sourcing 4-(4-Chlorophenyl)piperidin-4-ol from a dependable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures not only the quality of the intermediate but also the stability of the supply. This allows for uninterrupted production cycles and maintains the high standards expected in the pharmaceutical industry. The expertise of such manufacturers in custom synthesis and contract manufacturing further supports innovation and product development, providing tailored solutions to meet specific project needs. In essence, the selection of a high-quality 4-(4-Chlorophenyl)piperidin-4-ol supplier is a direct investment in the quality and success of the final pharmaceutical product.