In the relentless battle against bacterial infections, particularly those caused by multidrug-resistant organisms, the sophisticated interplay between antibiotics and their enhancers is paramount. Cilastatin Sodium, a pharmaceutical intermediate with the CAS number 1538-09-6, stands out as a critical component in this fight. Its primary function is to protect potent antibiotics like Imipenem from rapid degradation within the body, thereby extending their therapeutic lifespan and broadening their spectrum of activity. For procurement managers and R&D scientists in the pharmaceutical sector, understanding the value and sourcing reliable Cilastatin Sodium is a strategic imperative.

Imipenem, a carbapenem antibiotic, is a powerful weapon against a wide range of bacteria. However, without an inhibitor, it is quickly broken down by a renal enzyme called dehydropeptidase I. This is where Cilastatin Sodium steps in. By co-formulating with Imipenem, Cilastatin Sodium inhibits this enzyme, preventing the nephrotoxic breakdown of Imipenem. This synergy ensures that Imipenem remains active in the bloodstream for longer, offering robust protection against serious infections like pneumonia, urinary tract infections, and intra-abdominal sepsis. The demand for high-purity, GMP-certified Cilastatin Sodium is therefore consistently high among pharmaceutical manufacturers worldwide.

When sourcing this essential pharmaceutical intermediate, several factors are crucial for B2B buyers. Firstly, purity is non-negotiable. The provided material boasts a purity exceeding 99%, ensuring that the final drug product meets stringent regulatory requirements and delivers predictable therapeutic outcomes. Secondly, GMP (Good Manufacturing Practice) certification is a hallmark of quality and safety. Pharmaceutical intermediates produced under GMP conditions guarantee consistency, traceability, and a reduced risk of contamination. For companies looking to buy Cilastatin Sodium, partnering with a manufacturer that upholds these standards is essential.

The pricing of pharmaceutical raw materials is also a key consideration for procurement professionals. Understanding the market dynamics and securing competitive wholesale prices for Cilastatin Sodium can significantly impact the cost-effectiveness of drug production. Suppliers in China have emerged as major players in the global pharmaceutical intermediate market, offering a balance of quality, volume, and competitive pricing. Engaging with a reputable manufacturer from China ensures a stable supply chain and access to expert technical support.

For those involved in the formulation of life-saving antibiotics, the selection of a dependable supplier for Cilastatin Sodium (CAS 1538-09-6) is a decision that impacts patient safety and product efficacy. By prioritizing high purity, GMP compliance, and a strong supplier relationship, pharmaceutical companies can ensure the consistent availability of this vital intermediate, ultimately contributing to better patient care and market success. If you are looking to purchase Cilastatin Sodium or require a detailed quote, reaching out to established manufacturers and suppliers in the industry is the first step.