In the intricate world of pharmaceutical manufacturing, the selection of high-quality raw materials and intermediates is paramount to the success of drug development and production. Among these crucial compounds is 10,11-Dihydro-5H-dibenz[b,f]azepine, commonly known by its CAS number 494-19-9. This heterocyclic organic compound plays a pivotal role as a key intermediate in the synthesis of several significant pharmaceutical agents, particularly in the realm of central nervous system therapeutics. For procurement managers and R&D scientists, understanding its properties and reliable sourcing channels is essential.

Understanding 10,11-Dihydro-5H-dibenz[b,f]azepine's Significance

10,11-Dihydro-5H-dibenz[b,f]azepine is characterized by its distinctive tricyclic structure, which makes it an invaluable building block for synthesizing complex drug molecules. Its primary utility lies in its role as a precursor for widely prescribed medications, most notably antiepileptic drugs such as Carbamazepine and antispasmodic agents. The demand for this intermediate is directly linked to the global market for these essential pharmaceuticals, underscoring the importance of a stable and quality-assured supply chain.

Key Applications in Pharmaceutical Manufacturing

The versatility of 10,11-Dihydro-5H-dibenz[b,f]azepine allows it to be a foundational component in the creation of drugs that address significant health concerns. Its application extends to the synthesis of:

  • Antiepileptic Drugs: As a direct precursor to Carbamazepine, this intermediate is vital for manufacturing one of the most commonly used medications for epilepsy and bipolar disorder.
  • Antispastic Medications: It serves in the production of drugs used to treat muscle spasticity, providing therapeutic benefits for patients with various neurological conditions.
  • Other Therapeutic Agents: Research also indicates its utility in the synthesis of other drug classes, highlighting its broad applicability in medicinal chemistry.

Sourcing Strategies for Procurement Professionals

For B2B procurement managers and research scientists, securing a consistent supply of 10,11-Dihydro-5H-dibenz[b,f]azepine at competitive prices is a strategic imperative. When looking to buy this chemical intermediate, prioritizing suppliers with a proven track record in the fine chemical and pharmaceutical sectors is crucial. Manufacturers and suppliers based in China are often a preferred source due to their robust production capabilities and extensive export networks.

When evaluating potential suppliers, key considerations include:

  • Purity Levels: Ensuring the intermediate meets stringent purity requirements, typically 99% or higher, is non-negotiable for pharmaceutical applications.
  • Production Capacity: Verify the supplier's ability to meet your demand, whether for pilot studies or large-scale commercial production.
  • Regulatory Compliance: Confirm that the manufacturing processes adhere to international quality standards and that necessary documentation (like Certificates of Analysis) is readily available.
  • Logistics and Delivery: Understand their shipping capabilities, lead times, and reliability to ensure uninterrupted production.

Why Choose a Reputable Manufacturer?

Choosing a reputable manufacturer and supplier for 10,11-Dihydro-5H-dibenz[b,f]azepine (CAS 494-19-9) directly impacts the quality and cost-effectiveness of your final drug product. Companies specializing in pharmaceutical intermediates offer not only competitive pricing but also technical support and robust quality control. By establishing a strong relationship with a trusted manufacturer, you can ensure the uninterrupted supply of this critical material, mitigating risks and optimizing your operational efficiency. If you are looking to purchase this intermediate, engaging with experienced suppliers can provide valuable insights into market trends and best practices for its procurement.

In conclusion, 10,11-Dihydro-5H-dibenz[b,f]azepine is a cornerstone intermediate in the pharmaceutical industry. By understanding its importance and strategically sourcing it from reliable manufacturers, companies can effectively meet the demands for essential medicines worldwide. For any inquiries regarding pricing, availability, or bulk purchases, reaching out to dedicated suppliers is the first step towards securing your supply chain.