Pharmaceutical research and development is a dynamic field constantly seeking novel compounds and efficient synthesis routes for therapeutic agents. Within this landscape, 5-(4-Bromophenyl)-4,6-dichloropyrimidine (CAS: 146533-41-7) emerges as a significant chemical intermediate, primarily recognized for its indispensable role in the synthesis of Macitentan. Macitentan, a dual endothelin receptor antagonist, has gained traction for its therapeutic applications, particularly in managing pulmonary hypertension.

The utility of 5-(4-Bromophenyl)-4,6-dichloropyrimidine in drug discovery chemistry lies in its specific molecular structure, which can be further modified through various chemical reactions. This makes it a valuable starting material for medicinal chemists exploring new drug candidates. As a key intermediate, its purity and consistent supply are critical factors for researchers aiming to achieve reproducible results in their synthesis experiments. NINGBO INNO PHARMCHEM CO.,LTD., as a distinguished manufacturer in China, offers this compound with a high assay (u226598.0%), meeting the demanding requirements of pharmaceutical research.

Companies involved in the synthesis of Macitentan or exploring related pharmaceutical compounds often need to buy 5-(4-Bromophenyl)-4,6-dichloropyrimidine in significant quantities. Partnering with NINGBO INNO PHARMCHEM CO.,LTD. provides access to a reliable supply chain, ensuring that research projects are not hindered by material shortages. The company's expertise in fine chemical manufacturing and its strategic location in China enable competitive pricing and efficient delivery.

Moreover, understanding the handling and storage recommendations for 5-(4-Bromophenyl)-4,6-dichloropyrimidine, such as keeping it in a cool, ventilated place and protecting it from light, is part of the comprehensive support provided by suppliers like NINGBO INNO PHARMCHEM CO.,LTD. This detailed information is invaluable for research laboratories that must maintain precise environmental controls for their chemical reagents. Ultimately, the availability of high-quality intermediates like 5-(4-Bromophenyl)-4,6-dichloropyrimidine is foundational to the progress in pharmaceutical research.