Understanding the Synthesis and Properties of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
The advancement of medicinal chemistry relies heavily on the precise synthesis and understanding of complex organic molecules. 5-(4-Bromophenyl)-4,6-dichloropyrimidine (CAS: 146533-41-7) is one such molecule, playing a pivotal role as an intermediate in the production of Macitentan, a significant therapeutic agent. NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of providing this vital compound, ensuring its quality and availability for global pharmaceutical needs.
The synthesis of 5-(4-Bromophenyl)-4,6-dichloropyrimidine is a multi-step process that demands careful control over reaction conditions. Typically, it involves transformations of precursor molecules to build the pyrimidine ring and incorporate the necessary substituents. Researchers and manufacturers often seek detailed insights into these synthesis pathways to optimize yields and ensure the purity of the final product. The chemical structure, featuring a bromophenyl group attached to a dichloropyrimidine core, lends itself to further chemical modifications, making it a versatile intermediate.
Key physical and chemical properties are critical for handling and utilizing this compound effectively. As an off-white powder, it has specific solubility characteristics, often dissolving slightly in solvents like DMSO or chloroform. Its melting point and boiling point are important parameters for process development. Furthermore, the need for storage under inert gas at low temperatures (2-8°C) highlights its sensitivity and the necessity for careful handling to maintain its chemical integrity. This attention to detail in its properties is a hallmark of NINGBO INNO PHARMCHEM CO.,LTD.'s commitment to providing superior quality intermediates.
For entities looking to buy 5-(4-Bromophenyl)-4,6-dichloropyrimidine, understanding these synthetic routes and properties allows for informed procurement decisions. Whether for research laboratories or large-scale manufacturing, partnering with a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to consistent quality and technical support. This focus on comprehensive information and reliable supply solidifies its role in supporting pharmaceutical innovation.
The synthesis of 5-(4-Bromophenyl)-4,6-dichloropyrimidine is a multi-step process that demands careful control over reaction conditions. Typically, it involves transformations of precursor molecules to build the pyrimidine ring and incorporate the necessary substituents. Researchers and manufacturers often seek detailed insights into these synthesis pathways to optimize yields and ensure the purity of the final product. The chemical structure, featuring a bromophenyl group attached to a dichloropyrimidine core, lends itself to further chemical modifications, making it a versatile intermediate.
Key physical and chemical properties are critical for handling and utilizing this compound effectively. As an off-white powder, it has specific solubility characteristics, often dissolving slightly in solvents like DMSO or chloroform. Its melting point and boiling point are important parameters for process development. Furthermore, the need for storage under inert gas at low temperatures (2-8°C) highlights its sensitivity and the necessity for careful handling to maintain its chemical integrity. This attention to detail in its properties is a hallmark of NINGBO INNO PHARMCHEM CO.,LTD.'s commitment to providing superior quality intermediates.
For entities looking to buy 5-(4-Bromophenyl)-4,6-dichloropyrimidine, understanding these synthetic routes and properties allows for informed procurement decisions. Whether for research laboratories or large-scale manufacturing, partnering with a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to consistent quality and technical support. This focus on comprehensive information and reliable supply solidifies its role in supporting pharmaceutical innovation.
Perspectives & Insights
Molecule Vision 7
“5-(4-Bromophenyl)-4,6-dichloropyrimidine (CAS: 146533-41-7) is one such molecule, playing a pivotal role as an intermediate in the production of Macitentan, a significant therapeutic agent.”
Alpha Origin 24
“is at the forefront of providing this vital compound, ensuring its quality and availability for global pharmaceutical needs.”
Future Analyst X
“The synthesis of 5-(4-Bromophenyl)-4,6-dichloropyrimidine is a multi-step process that demands careful control over reaction conditions.”