The identification and utilization of specific chemical compounds are fundamental to progress in pharmaceutical research and development. For compounds like Oxidized Nifedipine, cataloged under CAS number 67035-22-7, their precise role and availability are critical for advancing our understanding of drug efficacy, safety, and metabolic pathways. This compound, a key metabolite of the widely prescribed drug Nifedipine, plays an indispensable part in various stages of pharmaceutical R&D.

Oxidized Nifedipine (CAS 67035-22-7) is primarily recognized as a significant metabolite found in human plasma following Nifedipine administration. Its formation involves enzymatic processes within the body, driven by cytochrome P450 enzymes like CYP3A4 and CYP3A5. Understanding these metabolic transformations is essential for predicting how a drug behaves in vivo, a process meticulously studied in pharmacokinetics. Researchers rely on high-purity Oxidized Nifedipine as a reference standard to accurately identify and quantify its presence in biological samples. This allows for a deeper comprehension of Nifedipine's ADME (Absorption, Distribution, Metabolism, and Excretion) profile.

Beyond its role in pharmacokinetic studies, Oxidized Nifedipine is also invaluable for drug metabolism research. It aids in elucidating the specific enzymatic pathways involved in Nifedipine breakdown, which can be crucial for predicting drug-drug interactions or understanding variations in patient responses. This detailed metabolic profiling is a key aspect of preclinical and clinical drug development, ensuring the safety and effectiveness of therapeutic agents.

Furthermore, the availability of Oxidized Nifedipine with a high purity level (often 98% or more) is critical for its application in quality control. It can serve as an impurity standard or reference material to ensure that Nifedipine formulations meet stringent regulatory requirements. This rigorous quality assurance process is vital for patient safety and the integrity of pharmaceutical products.

For researchers and procurement specialists, sourcing CAS 67035-22-7 requires partnering with reliable chemical manufacturers and suppliers. Companies globally seek dependable sources, often turning to established manufacturers in China known for their expertise in producing high-quality pharmaceutical intermediates and fine chemicals. When purchasing, key considerations include the purity of the compound, the availability of a detailed Certificate of Analysis (CoA), and the supplier's capacity for consistent and timely delivery. Competitive pricing is also a significant factor for research budgets.

In summary, Oxidized Nifedipine, designated by CAS 67035-22-7, is a vital compound in the pharmaceutical R&D ecosystem. Its function as a key Nifedipine metabolite makes it indispensable for pharmacokinetic and metabolism studies, as well as for stringent quality control. Ensuring access to this high-purity chemical from trusted suppliers is paramount for driving innovation and enhancing the safety and efficacy of pharmaceutical treatments.