For Research and Development (R&D) scientists in the pharmaceutical sector, the selection of appropriate building blocks is paramount to the success of new drug discovery and synthesis. (S)-(-)-3-Cyclohexenecarboxylic Acid (CAS 5708-19-0) stands out as a highly valuable intermediate due to its specific chiral configuration and versatile chemical functionalities. Its application in the synthesis of Active Pharmaceutical Ingredients (APIs) is a testament to its importance in medicinal chemistry.

The compound’s structure features a cyclohexene ring with a carboxylic acid group at the chiral center. This makes it an ideal starting material for the stereoselective synthesis of complex pharmaceutical molecules. For example, it has been cited as a reactant in the preparation of potent inhibitors of Factor Xa, a crucial enzyme in the blood coagulation cascade. The ability to introduce precise stereochemistry through such intermediates is critical for developing drugs with targeted efficacy and minimized side effects. R&D scientists seeking to buy these advanced materials can rely on manufacturers who guarantee high enantiomeric purity.

Beyond its role in Factor Xa inhibitor synthesis, (S)-(-)-3-Cyclohexenecarboxylic Acid serves as a versatile chiral synthon in the development of other therapeutic agents, including potential NSAIDs and prostaglandin analogs. Its dual functionality—the carboxylic acid group allowing for esterification or amidation, and the double bond enabling addition reactions—provides a broad scope for chemical modification. This versatility makes it an attractive intermediate for researchers exploring novel molecular scaffolds.

When looking to purchase (S)-(-)-3-Cyclohexenecarboxylic Acid, scientists often prioritize sourcing from reliable manufacturers who can provide consistent quality and detailed technical data. The availability of this intermediate from reputable Chinese suppliers, often with purity levels of 99% or higher, simplifies the procurement process. These manufacturers understand the critical needs of the pharmaceutical industry and strive to offer competitive pricing for bulk purchases, ensuring that R&D projects can progress efficiently from lab-scale synthesis to potential larger-scale production. Exploring the options from trusted chemical suppliers is a key step for any scientist involved in API development.