Estrone, identified by its CAS number 53-16-7, is a C18 steroid hormone that holds significant importance in the field of endocrinology and pharmaceutical research. As one of the three major endogenous estrogens, Estrone plays a distinct role in the human body, particularly after menopause where it becomes the predominant estrogen.

The synthesis of Estrone is a complex process involving enzymes like aromatase and 17β-hydroxysteroid dehydrogenase, occurring primarily in the ovaries, placenta, and even adipose tissues. This intricate biochemical pathway underscores its natural biological presence and its subsequent utility as a pharmaceutical intermediate.

In the realm of hormone therapy, Estrone is invaluable. It is instrumental in managing menopausal symptoms, addressing estrogen deficiency, and is considered for the prevention of osteoporosis in post-menopausal women. Understanding the dynamics of Estrone levels is crucial for effective treatment and improving the quality of life for many individuals.

Beyond therapeutic applications, Estrone is a critical tool in scientific research. Its involvement in the study of estrogen-related cancers, such as breast, endometrial, and ovarian cancers, allows researchers to explore preventative measures and therapeutic strategies. By investigating the role of Estrone in cancer cell growth and progression, scientists aim to develop more targeted and effective treatments.

Furthermore, Estrone is central to understanding reproductive physiology. Its influence on the menstrual cycle, ovulation, and pregnancy makes it a key subject in studies focused on fertility and hormonal regulation. Researchers often purchase Estrone to conduct in-vitro and in-vivo studies, seeking to unravel the complexities of the human reproductive system.

For those looking to buy Estrone for research or pharmaceutical synthesis, ensuring high purity and reliable sourcing is paramount. As a trusted supplier in China, we are committed to providing premium quality Estrone (CAS 53-16-7) that meets the rigorous demands of scientific research and pharmaceutical manufacturing. Our commitment ensures that your work benefits from a dependable supply of this essential hormone.