In the dynamic field of chemical manufacturing, the identification and consistent supply of key intermediates are crucial for innovation and efficient production. 2-Cyano-N,N-diethylacetamide, bearing the CAS number 26391-06-0, is a compound of significant utility, primarily recognized for its role in pharmaceutical synthesis and as a versatile building block in organic chemistry. This article explores its properties, applications, and provides guidance on sourcing this valuable chemical.

Understanding the Chemistry: 2-Cyano-N,N-diethylacetamide

2-Cyano-N,N-diethylacetamide is an organic molecule with the chemical formula C7H12N2O. Its structure is characterized by the presence of a cyano group (-C≡N) and an N,N-diethylacetamide moiety. This combination of functional groups endows it with specific reactivity, making it suitable for a range of chemical transformations. Typically appearing as a pale yellow to brown liquid, its purity is a key factor for its use in sensitive applications. An assay of 98.0% or higher is commonly specified, ensuring its efficacy in complex synthetic pathways.

Key Applications and Industry Relevance

The primary significance of 2-Cyano-N,N-diethylacetamide stems from its crucial role as an intermediate in the synthesis of Entacapone, a vital medication for Parkinson's disease patients. Entacapone functions by inhibiting catechol-O-methyltransferase, thereby prolonging the effect of levodopa. Beyond this critical pharmaceutical application, this compound serves as an excellent building block for synthesizing various N-heterocyclic compounds, which are foundational structures in many pharmaceuticals and agrochemicals. Its utility extends to research laboratories exploring new synthetic routes and developing novel chemical entities.

Sourcing Strategies for Professionals

For chemical engineers, R&D scientists, and procurement managers seeking to buy 2-Cyano-N,N-diethylacetamide, a strategic approach to sourcing is essential. Key factors to consider when evaluating suppliers and obtaining quotes include:

  • Product Purity and Specifications: Always verify the CAS number (26391-06-0) and the assay percentage (e.g., ≥98.0% via GC) to ensure the material meets your project's exact requirements.
  • Supplier Reliability and Origin: Partnering with established manufacturers and suppliers, particularly those based in major chemical production regions like China, can ensure consistent quality and a stable supply chain. Look for suppliers with strong quality management systems.
  • Competitive Pricing: Research market prices and obtain multiple quotes to negotiate the best possible price. Direct engagement with manufacturers often yields more cost-effective solutions than going through multiple intermediaries.
  • Technical Support and Documentation: A good supplier will offer comprehensive technical data, including Certificates of Analysis (CoA), and be available to answer technical queries.

Conclusion

2-Cyano-N,N-diethylacetamide (CAS: 26391-06-0) is a valuable intermediate that empowers innovation in pharmaceutical and organic synthesis. By understanding its chemical profile and adopting a well-informed sourcing strategy, businesses can ensure access to this essential compound. We are dedicated to providing high-quality 2-Cyano-N,N-diethylacetamide and supporting our clients' research and manufacturing endeavors. Contact us for your sourcing needs.