In the rigorous landscape of pharmaceutical manufacturing, the quality and reliability of chemical intermediates are non-negotiable. Thiophene-2-carboxylic acid, with CAS number 527-72-0, stands as a cornerstone intermediate, indispensable for the creation of numerous vital pharmaceutical compounds. Its distinctive chemical properties and versatile reactivity make it a prime candidate for advanced synthetic pathways. This article aims to provide procurement managers and research scientists with a comprehensive understanding of this compound and how to effectively source it.

Chemical Profile of Thiophene-2-carboxylic Acid

Thiophene-2-carboxylic acid, also known as 2-thenoic acid, is a heterocyclic organic compound that appears as a white powder. Its fundamental chemical formula is C5H4O2S, and it possesses a molecular weight of 128.15 g/mol. Key physical properties include a melting point typically recorded between 125-127 °C, signifying its solid state at standard room temperatures. The purity of the manufactured product, often exceeding 99%, is critical for its intended pharmaceutical applications, ensuring that subsequent reaction steps proceed predictably and without unwanted byproducts.

The Crucial Role in Pharmaceutical Synthesis

The significance of Thiophene-2-carboxylic acid within the pharmaceutical industry cannot be overstated. It serves as a fundamental building block, enabling the synthesis of a diverse array of active pharmaceutical ingredients (APIs). Researchers leverage its structure to introduce the thiophene moiety into drug candidates, a common strategy employed to enhance pharmacological activity, modify bioavailability, or improve metabolic stability. For instance, its derivative Suprofen demonstrates its direct utility in ophthalmic preparations. The demand for high-quality, consistently supplied Thiophene-2-carboxylic acid from reliable manufacturers is therefore substantial.

Finding a Trusted Manufacturer and Supplier

For pharmaceutical companies, securing a dependable supply chain for critical intermediates like Thiophene-2-carboxylic acid is paramount to maintaining production schedules and product quality. Sourcing from established manufacturers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., offers significant advantages, including competitive pricing and scalability. When evaluating potential suppliers, it is advisable to look for those who demonstrate a strong commitment to quality control, provide comprehensive technical documentation (like Certificates of Analysis), and offer responsive customer support. The ability to procure this chemical at a competitive price, especially in bulk, is a key consideration for cost-effective pharmaceutical production.

Key Considerations for Purchasing Thiophene-2-carboxylic Acid

When engaging with a supplier for Thiophene-2-carboxylic acid, several factors should be carefully assessed. The purity specifications must align with the intended application, especially for GMP-compliant processes. Availability for both R&D quantities and large-scale commercial orders is also important. Many manufacturers offer free samples, which is an excellent opportunity to validate product quality firsthand before placing a large purchase order. Understanding the typical price range for Thiophene-2-carboxylic acid will also aid in negotiation and budgeting. A robust relationship with a reputable chemical supplier ensures that your production lines remain uninterrupted and your end products meet the highest standards.

NINGBO INNO PHARMCHEM CO.,LTD. is a distinguished manufacturer and supplier of Thiophene-2-carboxylic acid (CAS: 527-72-0). We are dedicated to providing the pharmaceutical sector with intermediates of exceptional purity and reliability. Our commitment to quality, competitive pricing, and customer satisfaction makes us an ideal partner for your procurement needs. We encourage you to reach out to us for detailed product information, a quotation, and to discuss your specific requirements.