Trypsin, a critical serine protease, plays a fundamental role in numerous biological processes, from protein digestion to cell culture. Understanding and controlling its activity is often a key objective in biochemical research and various biotechnological applications. 4-Aminobenzamidine dihydrochloride (CAS 2498-50-2) has long been recognized as a potent and widely used inhibitor of trypsin. For scientists and procurement specialists, knowing how to effectively source and utilize this compound is essential.

The Mechanism of Trypsin Inhibition

4-Aminobenzamidine dihydrochloride functions as a competitive inhibitor of trypsin. Its structure mimics the substrate that trypsin normally binds to and cleaves. By binding to the active site of trypsin, it effectively blocks the enzyme's catalytic activity. This characteristic makes it an invaluable tool for researchers who need to precisely control trypsin activity in experimental settings, such as in protein purification protocols where preventing degradation is crucial, or in assays designed to study other proteases in the presence of trypsin.

Key Considerations When You Buy 4-Aminobenzamidine Dihydrochloride for Trypsin Inhibition

When your research demands reliable trypsin inhibition, selecting the right supplier for 4-Aminobenzamidine dihydrochloride is critical. Here are key factors to consider:

  • Purity: For effective enzyme inhibition, high purity is non-negotiable. Look for products specified with at least 98% HPLC purity. Impurities could interfere with the enzyme or lead to erroneous results.
  • Supplier Reliability: Partner with manufacturers and suppliers known for consistent quality and stable supply chains. A trusted supplier ensures you can always buy 4-Aminobenzamidine dihydrochloride when you need it.
  • Form and Storage: Typically supplied as a white powder, proper storage (often refrigerated, 2-8°C) is essential to maintain its activity and shelf life. Check the supplier's recommended storage conditions.
  • Cost-Effectiveness: While quality is paramount, competitive pricing, especially for bulk purchases, is important for budget management. Requesting quotes from multiple suppliers can help identify the best value.
  • Technical Support: A supplier that can provide technical data sheets (TDS) and safety data sheets (SDS) and answer questions about application is highly beneficial.

Applications Beyond Trypsin Inhibition

While its role as a trypsin inhibitor is prominent, 4-Aminobenzamidine dihydrochloride also exhibits activity against other proteases, such as urokinase. This broader enzymatic inhibitory profile further enhances its utility in research, particularly in studies involving the plasminogen activation system.

For those seeking to purchase 4-Aminobenzamidine dihydrochloride for precise trypsin inhibition or other biochemical research needs, our company offers a reliable source with guaranteed high purity and competitive pricing. We understand the critical nature of these reagents and are dedicated to supporting your scientific endeavors. Reach out to us for quotes and samples.