2-Chloro-1,4-naphthoquinone, identified by its CAS number 1010-60-2, is a compound of significant interest in the chemical and pharmaceutical industries. Characterized by its bright yellow crystalline powder appearance, this substance possesses a unique molecular structure (C10H5ClO2) that dictates its valuable chemical properties. With a density of 1.42 g/cm³ and a boiling point of 308°C at 760 mmHg, it demonstrates considerable stability under various processing conditions.

The primary driver for the demand of 2-Chloro-1,4-naphthoquinone is its role as a critical Atovaquone intermediate. Atovaquone is a widely used drug for treating parasitic infections such as malaria and certain types of pneumonia. The synthesis pathway relies on the specific reactivity of 2-Chloro-1,4-naphthoquinone to build the complex molecular structure of Atovaquone. This makes its purity, typically specified at a minimum of 98%, of paramount importance for drug efficacy and safety.

Manufacturers and suppliers, particularly those based in China, play a pivotal role in ensuring a steady global supply of this compound. The expertise of Chinese manufacturers in producing fine chemicals and pharmaceutical intermediates is well-established, offering both quality assurance and competitive pricing. When searching for a 2-Chloro-1,4-naphthoquinone manufacturer, it is essential to prioritize those with robust quality control systems and a proven track record. The price of 2-Chloro-1,4-naphthoquinone can vary based on purity and order volume, making it crucial for buyers to compare options and secure a reliable source.

The physical properties, such as its solid form and specific melting point range (though not explicitly detailed in all sources), along with its solubility characteristics, are important considerations for industrial handling and application. Proper storage, typically in cool, dry, and well-closed containers away from moisture and strong light, is essential to maintain its integrity. For any company requiring this key building block, understanding these properties and sourcing from reputable 2-Chloro-1,4-naphthoquinone suppliers is fundamental to successful operations.