For chemists, researchers, and procurement specialists involved in fine chemical synthesis, understanding the fundamental properties and applications of key intermediates is crucial. 2-Pyridinecarboxaldehyde (CAS 1121-60-4) is one such compound, a versatile pyridine derivative with significant utility in both the pharmaceutical and agrochemical industries. This article provides a detailed overview of its characteristics, primary uses, and essential considerations for sourcing.

Chemical Identity and Properties:
2-Pyridinecarboxaldehyde, also known by synonyms like picolinaldehyde or 2-formylpyridine, is an organic compound with the molecular formula C6H5NO and a molecular weight of 107.11. It is typically presented as a light yellow to light brown liquid. Key physical properties reported include a melting point between -21–22°C and a boiling point of approximately 181°C. Its density is around 1.126 g/mL at 25°C. The compound is sensitive to air and light, necessitating proper storage conditions, typically in a cool, dry, well-ventilated place, with containers tightly closed.

Primary Applications:
The primary significance of 2-Pyridinecarboxaldehyde lies in its role as a critical intermediate in the synthesis of various high-value products:

  • Pharmaceuticals: It is a key raw material for the production of the organophosphate detoxification drug PAM (pralidoxime) and the laxative bisacodyl. The demand for high-purity 2-Pyridinecarboxaldehyde is directly linked to the production of these essential medicines.
  • Agrochemicals: The compound is utilized in the development of various agrochemical products, contributing to the creation of advanced pesticides, herbicides, and plant growth regulators.
  • Organic Synthesis: As a heterocyclic aldehyde, it serves as a fundamental building block for constructing more complex organic molecules in research and industrial settings.

Sourcing and Supply Chain Considerations:
For businesses looking to buy 2-Pyridinecarboxaldehyde, reliable sourcing is paramount. China has become a primary manufacturing hub for such fine chemicals, offering both competitive pricing and substantial production capacity. When selecting a supplier, prioritize manufacturers that offer:

  • High Purity: Look for guaranteed purity levels, such as ≥98.0% (GC), essential for downstream synthesis.
  • Consistent Quality: Ensure the supplier has robust quality control processes in place to maintain product consistency.
  • Reliable Supply: Confirm their production capacity and ability to meet your volume requirements for both R&D and large-scale manufacturing.
  • Competitive Pricing: Obtaining direct quotes from manufacturers can help secure the best possible price for bulk purchases.
  • Regulatory Compliance: Check for adherence to relevant industry standards and availability of necessary documentation (CoA, MSDS).

In conclusion, 2-Pyridinecarboxaldehyde (CAS 1121-60-4) is a compound of significant industrial importance. By understanding its properties and applications, and by partnering with trusted manufacturers and suppliers, companies can ensure a stable and cost-effective supply for their critical synthetic processes. We encourage you to contact us for a quote on your bulk purchasing needs.