In the intricate world of pharmaceutical manufacturing, the role of high-quality intermediates cannot be overstated. These chemical building blocks are the foundation upon which life-saving medications are built. Among these critical components is 2-Thioadenosine, identified by its CAS number 43157-50-2. This compound has garnered significant attention for its indispensable role in the synthesis of advanced cardiovascular drugs, particularly antiplatelet agents like Cangrelor.

What is 2-Thioadenosine?

2-Thioadenosine, also known by synonyms such as 2-Mercaptoadenosine or Adenosine-2-thione, is a nucleoside derivative. Chemically, it is characterized by a purine ring system where a sulfur atom replaces an oxygen atom at the 2-position. This structural modification imbues it with unique chemical properties that are vital for its downstream applications in medicinal chemistry. As a pale yellow to yellow solid, its purity and consistent quality are paramount for pharmaceutical manufacturers and researchers seeking reliable raw materials.

The Crucial Role in Cangrelor Synthesis

The primary application of 2-Thioadenosine in the pharmaceutical industry is its function as a key intermediate in the production of Cangrelor. Cangrelor is a potent, intravenous P2Y12 platelet receptor antagonist. It is clinically used to prevent or reduce the risk of thrombosis, particularly in patients undergoing percutaneous coronary interventions (PCI), such as stenting procedures. The efficacy of Cangrelor hinges on the precise synthesis involving intermediates like 2-Thioadenosine. For any pharmaceutical company looking to buy 2-Thioadenosine for this purpose, partnering with a reputable manufacturer in China like NINGBO INNO PHARMCHEM is crucial to ensure a stable supply chain and competitive price.

Beyond Cangrelor: Biological Significance and Research Potential

While its role in Cangrelor synthesis is well-established, 2-Thioadenosine also holds biological significance. In biological systems, adenosine derivatives are known to regulate the synthesis and degradation of essential biomolecules such as DNA, RNA, and proteins. They also play a part in cellular signaling pathways, influencing cell growth, proliferation, and apoptosis. Furthermore, these compounds contribute to maintaining cellular redox balance and managing oxidative stress. This broad biological relevance suggests potential research avenues for 2-Thioadenosine beyond its current primary application, perhaps in developing other therapeutic agents or as a tool in biochemical research.

Sourcing High-Quality 2-Thioadenosine from a Trusted Supplier

For researchers and procurement managers in the pharmaceutical sector, sourcing intermediates that meet stringent quality specifications is non-negotiable. NINGBO INNO PHARMCHEM CO.,LTD. is committed to being a leading supplier of 2-Thioadenosine, offering products manufactured to high standards. We understand the importance of consistent quality, timely delivery, and competitive pricing for our clients. Whether you are involved in early-stage drug discovery or large-scale API production, our team is dedicated to meeting your needs. If you are looking to purchase 2-Thioadenosine, we encourage you to request a quote and sample to experience the quality and service we provide.

In conclusion, 2-Thioadenosine (CAS 43157-50-2) is more than just a chemical compound; it is a vital enabler of critical cardiovascular therapies. Its availability from reliable manufacturers ensures the continuity of research and production, ultimately contributing to improved patient outcomes. As a dedicated pharmaceutical intermediate manufacturer, NINGBO INNO PHARMCHEM is proud to contribute to the advancement of healthcare through the provision of high-purity chemical solutions.