In the complex world of pharmaceutical manufacturing, understanding the role of various chemical compounds is paramount. One such compound, 3-Oxo Atorvastatin (CAS 887196-30-7), holds significant importance, particularly in the production of Atorvastatin, a widely prescribed medication for managing cholesterol levels. As a key pharmaceutical intermediate and a known impurity, its reliable supply and high purity are critical for drug manufacturers and researchers worldwide.

Atorvastatin, a statin, works by inhibiting HMG-CoA reductase, an enzyme crucial for cholesterol synthesis. The synthesis of Atorvastatin is a multi-step process, and like many complex organic syntheses, it can generate byproducts. 3-Oxo Atorvastatin is one such byproduct that is frequently encountered. Its chemical formula is C33H33FN2O5, and it possesses a molecular weight of approximately 556.62 g/mol. The presence of a β-keto group at the 3-position distinguishes it from the parent drug.

For pharmaceutical companies, the accurate identification and quantification of impurities are as vital as the synthesis of the active pharmaceutical ingredient (API) itself. Regulatory bodies, such as the European Pharmacopoeia (EP) and the United States Pharmacopeia (USP), set strict limits for impurities in drug products. 3-Oxo Atorvastatin is listed as Impurity O in the EP monograph for Atorvastatin Calcium, with specific permissible limits. This necessitates that manufacturers have access to high-purity 3-Oxo Atorvastatin as a reference standard for analytical method development, validation, and routine quality control testing. By using a reliable impurity standard manufacturer, companies can ensure the safety and efficacy of their drug products.

The synthesis pathways leading to 3-Oxo Atorvastatin are often studied to optimize the manufacturing process of Atorvastatin and minimize the formation of this impurity. Understanding these pathways allows for process improvements, leading to higher yields of the desired API and reduced purification challenges. For example, studies have investigated how different reaction conditions in batch reactors or the adoption of continuous flow synthesis can influence the generation of such impurities. Researchers often buy 3-oxo atorvastatin manufacturer China to source this critical intermediate for their studies.

As a dedicated manufacturer and supplier of 3-Oxo Atorvastatin in China, we are committed to providing pharmaceutical professionals with the high-purity material they need. Our product, with a guaranteed purity of 98%, serves as an indispensable tool for R&D departments, quality control laboratories, and API manufacturers. Whether you are developing new analytical methods, validating existing ones, or ensuring batch-to-batch consistency, our reliable supply chain and competitive pricing for 3-Oxo Atorvastatin make us your ideal partner.

Sourcing crucial pharmaceutical intermediates and impurities from a trusted supplier in China offers significant advantages, including cost-effectiveness and access to specialized chemical expertise. We understand the importance of a stable and dependable supply for uninterrupted production. Therefore, if you are looking to order 3-oxo atorvastatin or seeking a dependable pharmaceutical intermediate supplier, we invite you to contact us for a quote and to learn more about our high-quality offerings.