For professionals engaged in organic synthesis and pharmaceutical manufacturing, understanding the nuances of key chemical intermediates is fundamental. 6-Methyleneandrost-4-ene-3,17-dione, identified by CAS number 19457-55-7, stands out as a significant steroid intermediate with diverse applications. This compound, with its empirical formula C20H26O2 and a molecular weight of 298.42, possesses a distinct chemical structure that makes it valuable in specialized synthesis projects.

The chemical properties of 6-Methyleneandrost-4-ene-3,17-dione are well-documented. It typically appears as a pale yellow solid, with a melting point often cited in the range of 162-164 °C. Its density is approximately 1.11 g/cm³, and it has a high boiling point of around 450.8 °C at standard pressure, with a flash point of 168 °C. These physical characteristics are crucial for handling, storage, and processing in industrial settings. The synthesis of this compound often involves modifications to the androstenedione structure, employing reagents like formaldehyde, highlighting its nature as a derived steroid.

As a steroid intermediate, 6-Methyleneandrost-4-ene-3,17-dione is instrumental in the production of various steroidal compounds. Its presence is significant in pathways leading to pharmaceutical agents, particularly those related to hormonal therapies. For example, it is recognized as a related compound or impurity in the synthesis of Exemestane, an important aromatase inhibitor used in breast cancer treatment. Therefore, procurement of high-purity 6-Methyleneandrost-4-ene-3,17-dione is essential for quality control and research in this area.

When sourcing this chemical, understanding the global manufacturing landscape is beneficial. China is a prominent hub for the production of fine chemicals and pharmaceutical intermediates. Buyers looking to purchase CAS 19457-55-7 can find numerous manufacturers offering this product. The price of 6-Methyleneandrost-4-ene-3,17-dione can vary based on purity, quantity, and the specific supplier. It is advisable to obtain multiple quotes and compare specifications from reputable suppliers to ensure you are getting the best value and quality.

Engaging with experienced manufacturers and distributors ensures that you receive not only the chemical itself but also the necessary documentation and support. Whether for advanced chemical synthesis, pharmaceutical research, or impurity profiling, 6-Methyleneandrost-4-ene-3,17-dione is a compound of considerable importance. We are dedicated to providing this essential building block to meet the demanding requirements of the global chemical and pharmaceutical industries.