For chemists and procurement specialists in the chemical industry, understanding the properties and applications of key organic intermediates is fundamental to successful synthesis and product development. 1-Bromo-4-chlorobutane, identified by its CAS number 6940-78-9, is a versatile bifunctional alkyl halide that plays a significant role across various chemical manufacturing sectors. This article aims to provide a comprehensive overview of this compound, its properties, uses, and guidance on sourcing from reliable suppliers.

Chemical Profile of 1-Bromo-4-Chlorobutane (CAS 6940-78-9)

1-Bromo-4-chlorobutane (C4H8BrCl) is characterized by a four-carbon chain with a bromine atom at one end and a chlorine atom at the other. This dual halogenation makes it a reactive intermediate capable of undergoing various substitution and coupling reactions. Typically supplied as a colorless to pale yellow liquid, its molecular weight is approximately 171.46 g/mol. The EINECS number associated with this compound is 230-089-3.

The bifunctional nature of 1-Bromo-4-chlorobutane is its primary asset. The bromine atom is generally more reactive than the chlorine atom in nucleophilic substitution reactions, allowing for selective functionalization. This selective reactivity is highly prized in multi-step organic synthesis, where precise control over reaction pathways is crucial.

Applications Across Industries

  • Pharmaceutical Intermediates: As mentioned previously, it's a critical building block for APIs, facilitating the construction of complex drug molecules.
  • Agrochemicals: It can be used in the synthesis of certain pesticides and herbicides.
  • Specialty Chemicals: Its reactivity makes it useful in the development of performance materials, polymers, and other specialized chemical products.
  • Research and Development: In academic and industrial R&D settings, it serves as a convenient reagent for exploring new synthetic routes and discovering novel compounds.

Sourcing 1-Bromo-4-Chlorobutane: What Buyers Need to Know

When seeking to buy 1-Bromo-4-chlorobutane, particularly from international manufacturers in China, several factors are critical for a successful procurement:

  • Verified Purity: Look for suppliers who guarantee a high assay, typically 99% or greater, and can provide a Certificate of Analysis (COA).
  • Supplier Credibility: Prioritize manufacturers with established export experience, positive buyer reviews, and transparent business practices. Information regarding their production capacity (e.g., 200 tons/month) and quality assurance systems is important.
  • Competitive Pricing and MOQ: Obtaining quotes from multiple suppliers and comparing them is advisable, while always considering the overall value proposition beyond just the price.
  • Logistics and Packaging: Ensure the supplier offers suitable packaging (e.g., drums) and reliable shipping options to meet your delivery timelines.

Engaging directly with manufacturers allows for better price negotiation and a clearer understanding of lead times. Companies that offer sample requests can be particularly helpful for validation before committing to larger orders. Therefore, when you need CAS 6940-78-9, focus on finding a supplier that can consistently deliver quality and meet your specific requirements.