As manufacturers and suppliers of fine chemicals and pharmaceutical intermediates, we understand the critical importance of every compound we produce. (E)-4-Hydroxycrotonic Acid (CAS: 24587-49-3) is a prime example of an intermediate that requires meticulous attention to quality and a deep understanding of its applications. This article delves into the compound from a manufacturer's perspective, highlighting its characteristics, its indispensable role in key syntheses, and our commitment to delivering excellence.

The Genesis of Quality: Manufacturing (E)-4-Hydroxycrotonic Acid

At NINGBO INNO PHARMCHEM CO.,LTD., we produce (E)-4-Hydroxycrotonic Acid with a focus on precision and purity. Our process yields a light yellow crystalline powder, a testament to the controlled synthesis and purification steps undertaken. The target assay purity of ≥98.0% is not merely a specification but a guarantee of performance for our clients in the pharmaceutical and chemical industries. The compound's stable properties, including its high boiling point (338.7ºC) and flash point (172.9ºC), are critical indicators of its quality and safe handling characteristics. We ensure that storage recommendations—in a cool, ventilated environment—are rigorously followed to maintain this integrity throughout the supply chain.

Application Spotlight: The Role in Neratinib Synthesis

One of the most significant applications of (E)-4-Hydroxycrotonic Acid is its function as a vital intermediate in the synthesis of Neratinib (CAS: 698387-09-6). Neratinib is a critical pharmaceutical agent, and its production demands intermediates of the highest caliber. The precise molecular structure of (E)-4-Hydroxycrotonic Acid, C4H6O3, allows for specific chemical transformations that are essential for building the complex architecture of Neratinib. Our commitment as a manufacturer is to provide this compound with consistent purity, thereby supporting the efficient and reliable production of life-saving medications. Companies looking to buy this intermediate are assured of our dedication to quality, which directly contributes to the success of their downstream processes.

Beyond Pharmaceuticals: Broader Synthetic Utility

While its pharmaceutical applications are prominent, the reactivity inherent in the hydroxyl and carboxylic acid groups of (E)-4-Hydroxycrotonic Acid makes it a versatile building block for broader organic synthesis. Chemists can leverage this compound for creating novel molecules, specialty chemicals, and advanced materials. As a manufacturer, we aim to be a dependable partner for all these diverse needs, offering scalable production and responsive service. Whether you require small batches for R&D or large volumes for commercial production, our facility is equipped to meet your demands.

Partnering for Success

For those seeking to buy (E)-4-Hydroxycrotonic Acid, choosing a manufacturer with a strong emphasis on quality assurance and a clear understanding of its applications is key. NINGBO INNO PHARMCHEM CO.,LTD. embodies these principles. We are more than just a supplier; we are a manufacturing partner dedicated to supporting your innovation and production goals. Connect with us to learn more about our capabilities and how we can provide you with high-quality (E)-4-Hydroxycrotonic Acid, ensuring consistency and reliability for your critical chemical needs.