Understanding Gefitinib Synthesis: The Role of 4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile
The development and production of targeted cancer therapies like Gefitinib involve complex synthetic pathways that rely heavily on high-quality chemical intermediates. Among these, 4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile (CAS 675126-26-8) stands out as a crucial building block. For pharmaceutical companies and R&D institutions, sourcing this compound reliably and with assured purity is paramount to ensuring the efficacy and safety of the final Active Pharmaceutical Ingredient (API).
Gefitinib, a potent inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, has revolutionized the treatment of certain non-small cell lung cancers. Its synthesis is a multi-step process, and the quality of each intermediate directly impacts the overall yield and purity of the final drug product. 4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile serves as a key precursor, providing a foundational structure that is further elaborated through chemical transformations.
As a leading manufacturer and supplier of pharmaceutical intermediates, understanding the needs of the B2B chemical market is our priority. We recognize that procurement managers, R&D scientists, and formulation chemists require not just the chemical itself, but also consistent quality, competitive pricing, and stable supply chains. When you seek to buy 4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile, you are looking for a partner who can deliver these essential elements.
The compound's specifications, including its yellow powder appearance and a purity assay of ≥98.0%, are critical metrics. Its molecular formula (C15H19N3O5) and molecular weight (321.328) are standard references for chemists. The physical properties, such as a density of 1.3 g/cm³ and a boiling point of 522.3°C, are also important for handling and processing. Packaging in 25 kg drums makes it suitable for bulk orders.
For organizations engaged in pharmaceutical synthesis, the importance of a reliable supplier of Gefitinib intermediates cannot be overstated. Sourcing from experienced manufacturers in China offers a significant advantage in terms of cost-effectiveness and production capacity. We invite you to connect with us to discuss your requirements for 4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile. Whether you are performing initial research or scaling up production, our high-purity intermediate is available to meet your demands. Procuring quality intermediates like this is a strategic step towards successful drug development and manufacturing.
Perspectives & Insights
Future Origin 2025
“As a leading manufacturer and supplier of pharmaceutical intermediates, understanding the needs of the B2B chemical market is our priority.”
Core Analyst 01
“We recognize that procurement managers, R&D scientists, and formulation chemists require not just the chemical itself, but also consistent quality, competitive pricing, and stable supply chains.”
Silicon Seeker One
“When you seek to buy 4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile, you are looking for a partner who can deliver these essential elements.”