Hydrocinnamoyl Chloride, identified by its CAS number 645-45-4, is a chemical compound that plays a pivotal role in various industrial and research applications, primarily as a fine chemical and pharmaceutical intermediate. Understanding its journey from synthesis to global availability provides valuable insight into its significance.

The synthesis of Hydrocinnamoyl Chloride typically begins with 3-phenylpropionic acid, which is then reacted with a chlorinating agent like oxalyl chloride. This process is crucial for creating the reactive acyl chloride functional group. The resulting product is generally a clear, colorless to light yellow liquid with a high purity, commonly exceeding 98.0% as determined by GC. Its chemical properties, such as its reactivity with moisture and nucleophiles, dictate its handling and application methods.

The primary application of Hydrocinnamoyl Chloride is its use as a pharmaceutical intermediate. It is a key component in the synthesis of various drug compounds, including those with antiviral and antitumor activities. This makes it a sought-after material in the pharmaceutical research and manufacturing sectors. Beyond pharmaceuticals, its versatility as an organic synthesis reagent allows it to be used in the creation of other specialty chemicals.

The global supply chain for Hydrocinnamoyl Chloride involves manufacturers and suppliers from various regions, with China being a significant contributor. When companies look to buy Hydrocinnamoyl Chloride, they often seek reliable suppliers who can guarantee product quality, consistent purity, and timely delivery. Factors such as proper packaging (e.g., fluorinated bottles or drums) and adherence to storage recommendations (e.g., under inert gas, away from moisture) are critical for maintaining product integrity.

In conclusion, Hydrocinnamoyl Chloride (CAS 645-45-4) is a vital fine chemical whose importance is underscored by its critical role in pharmaceutical synthesis and its broad utility in organic chemistry. Its availability through established global supply chains ensures that researchers and manufacturers can access this essential compound for their diverse needs.