Understanding N-Cbz-Glycine Ethyl Ester for Peptide Synthesis
As a discerning procurement manager or a dedicated research scientist in the pharmaceutical and biotech sectors, you understand the critical importance of high-quality building blocks for successful synthesis. Among these essential components, N-Cbz-Glycine Ethyl Ester (CAS 1145-81-9) stands out as a key player, particularly in the intricate field of peptide synthesis. This article aims to provide you with a clear understanding of this compound, its applications, and why partnering with a reputable manufacturer for your N-Cbz-Glycine Ethyl Ester purchase is paramount.
What is N-Cbz-Glycine Ethyl Ester?
N-Cbz-Glycine Ethyl Ester, also known by synonyms such as Ethyl 2-(((benzyloxy)carbonyl)amino)acetate or Z-Gly-Gly-Oet, is an organic compound widely utilized as a protective group in organic synthesis. Its primary function is to protect the amino group of glycine, allowing for selective chemical reactions to occur at other sites of a molecule. This protection is crucial in multi-step synthesis, preventing unwanted side reactions and ensuring the desired product is formed with high purity.
Key Properties and Applications in Synthesis
This compound typically presents as a white powder, with purity levels often exceeding 98% or 99%. Its physical and chemical properties, such as density and refractive index, are well-documented, providing a solid foundation for its use in laboratory settings and industrial production. The core application lies in its role as a pharmaceutical intermediate. Specifically, it is invaluable in:
- Peptide Synthesis: In the construction of peptide chains, the amino group of each amino acid must be temporarily protected. N-Cbz-Glycine Ethyl Ester serves this purpose for glycine, allowing for controlled coupling reactions. Its presence facilitates the formation of specific peptide bonds, leading to the synthesis of therapeutic peptides used in various medical treatments. If you are looking to buy N-Cbz-Glycine Ethyl Ester for your peptide research, ensure you source from a manufacturer with a proven track record.
- Organic Synthesis: Beyond peptides, it functions as a versatile reagent in a broad spectrum of organic synthesis pathways. Its ability to selectively protect functional groups makes it a valuable tool for chemists designing complex molecules for pharmaceuticals, agrochemicals, and other fine chemical applications.
Why Source from a Reliable China Manufacturer?
When sourcing critical raw materials like N-Cbz-Glycine Ethyl Ester, quality and reliability are non-negotiable. Partnering with established Chinese manufacturers offers several advantages, including competitive pricing and access to large-scale production capabilities. A reputable supplier will not only provide a high-purity product but also detailed specifications, safe handling instructions, and a stable supply chain. If you're considering a purchase, look for suppliers that can offer certificates of analysis and demonstrate consistent quality batch after batch. Understanding the N-Cbz-Glycine Ethyl Ester price in the market can be facilitated by direct inquiry to trusted suppliers.
Storage and Handling Considerations
Proper storage is essential to maintain the integrity of N-Cbz-Glycine Ethyl Ester. It should be kept in a tightly closed container, stored in a cool, dry place, away from direct sunlight and incompatible materials. Following these guidelines ensures the compound remains effective for your synthesis needs.
For procurement managers and R&D scientists seeking a dependable source for N-Cbz-Glycine Ethyl Ester, engaging with experienced manufacturers in China can provide the quality, quantity, and competitive pricing necessary for project success. Consider your N-Cbz-Glycine Ethyl Ester purchase as an investment in your research and development pipeline.
Perspectives & Insights
Chem Catalyst Pro
“Its primary function is to protect the amino group of glycine, allowing for selective chemical reactions to occur at other sites of a molecule.”
Agile Thinker 7
“This protection is crucial in multi-step synthesis, preventing unwanted side reactions and ensuring the desired product is formed with high purity.”
Logic Spark 24
“Key Properties and Applications in Synthesis This compound typically presents as a white powder, with purity levels often exceeding 98% or 99%.”