For pharmaceutical R&D and manufacturing, understanding the cost of critical raw materials is essential for budgeting and project planning. (S)-3-Hydroxytetrahydrofuran (CAS 86087-23-2), a vital chiral intermediate, has a price that fluctuates based on several key factors. For procurement specialists and R&D scientists looking to purchase this compound, gaining insight into these factors can lead to more strategic sourcing decisions.

Factors Influencing (S)-3-Hydroxytetrahydrofuran Pricing

  • Purity and Enantiomeric Excess: The higher the purity and enantiomeric excess (ee) of the compound, the more complex and costly the synthesis and purification process. Pharmaceutical-grade material (≥99% purity) will naturally command a higher price than research-grade material.
  • Scale of Production: As with most chemicals, the price per unit of (S)-3-Hydroxytetrahydrofuran generally decreases with larger order volumes. Bulk purchases benefit from economies of scale in manufacturing, raw material procurement, and logistics.
  • Raw Material Costs: The availability and cost of precursor chemicals and catalysts used in the synthesis of (S)-3-Hydroxytetrahydrofuran directly impact the final product price. Fluctuations in these upstream markets can influence the overall cost.
  • Manufacturing Complexity: The synthesis of chiral intermediates often involves multi-step processes, specialized equipment, and skilled labor, all of which contribute to the manufacturing cost.
  • Regulatory Compliance and Quality Control: Manufacturers adhering to strict GMP (Good Manufacturing Practice) guidelines and robust quality control measures incur higher operational costs, which are reflected in the product's price but essential for pharmaceutical applications.

Navigating Bulk Orders and Quotes

When planning for bulk orders of (S)-3-Hydroxytetrahydrofuran, obtaining detailed quotes from reliable manufacturers is crucial. NINGBO INNO PHARMCHEM CO.,LTD., as a direct manufacturer, offers competitive pricing, especially for substantial quantities. When requesting a quote, be sure to specify the required purity, quantity, and any specific analytical documentation needed. This will allow the supplier to provide an accurate and tailored quotation.

Strategic Sourcing for Cost-Effectiveness

Sourcing from manufacturers in China can often provide a cost advantage without compromising on quality, provided the supplier has stringent quality control systems in place. By engaging directly with manufacturers, you can often bypass intermediary markups, leading to more favorable pricing for your bulk requirements. Understanding the market dynamics and establishing relationships with trustworthy suppliers will ensure you secure the best possible price for this indispensable pharmaceutical intermediate.

In summary, while the price of (S)-3-Hydroxytetrahydrofuran is influenced by numerous factors, strategic sourcing and bulk purchasing from reputable manufacturers are key to achieving cost-effectiveness in pharmaceutical development.