For professionals in the pharmaceutical and fine chemical industries, a thorough understanding of chemical compounds is essential for efficient research and procurement. This article delves into the properties and applications of 7-Bromo-1,2,3,4-tetrahydrocyclopenta[b]indole, a compound identified by its CAS number 164736-47-4.

Chemical Identity and Structure

7-Bromo-1,2,3,4-tetrahydrocyclopenta[b]indole is classified as a heterocyclic compound, specifically an indole derivative. Its molecular formula is C11H10BrN, and its molecular weight is approximately 236.11 g/mol. The structure features a fused ring system that includes a partially saturated cyclopentane ring attached to an indole moiety, with a bromine atom positioned at the 7-position of the indole ring. This specific arrangement of atoms dictates its chemical behavior and potential applications in synthesis.

Key Physicochemical Properties

The compound typically exists as a solid at room temperature. While specific physical characteristics can vary slightly based on purity and manufacturing batches, common data points include:

  • Density: Around 1.41-1.60 g/cm³ (predicted).
  • Boiling Point: Approximately 265.9 °C at 760 mmHg (predicted), indicating moderate volatility.
  • Flash Point: Around 114.6 °C (predicted), suggesting it requires careful handling around heat sources.
  • Purity: Available from manufacturers and suppliers at purity levels of 95% and 98%, crucial for reproducible experimental outcomes.

These properties are important for procurement managers to consider when assessing storage, handling, and application suitability. For researchers, knowing these parameters helps in designing experiments effectively.

Applications and Research Potential

7-Bromo-1,2,3,4-tetrahydrocyclopenta[b]indole serves primarily as an intermediate in organic synthesis, particularly within the pharmaceutical sector. Its structural features make it an excellent starting material for:

  • Drug Discovery: As a scaffold for developing novel pharmaceutical agents, its indole core is present in many biologically active molecules.
  • Medicinal Chemistry: The bromine atom allows for regioselective functionalization, facilitating the synthesis of diverse compound libraries for screening.
  • Materials Science: Certain indole derivatives find applications in the development of organic electronic materials.

Where to Buy and How to Procure

When sourcing this chemical, it is advisable to buy from established manufacturers who can provide a Certificate of Analysis (CoA) detailing the purity and specifications. For procurement managers looking for reliable suppliers, exploring options from manufacturers in China can offer competitive pricing and direct access to products. Understanding the market for 7-Bromo-1,2,3,4-tetrahydrocyclopenta[b]indole involves comparing prices and lead times from various vendors. Requesting quotes for bulk purchases is a common strategy to secure better terms.

In summary, 7-Bromo-1,2,3,4-tetrahydrocyclopenta[b]indole is a valuable chemical intermediate. Its well-defined properties and broad synthetic utility make it a key compound for researchers and procurement specialists in the chemical and pharmaceutical industries. Ensuring a reliable supply of high-purity material is essential for the success of research and development projects.