Pyridine-3-sulfonyl Chloride, identified by its CAS number 16133-25-8, is a chemical compound of significant interest in the pharmaceutical and fine chemical industries. As a colorless to yellow liquid, its precise chemical structure and properties make it an indispensable building block for various synthesis pathways. For researchers and procurement managers, understanding its characteristics is the first step towards efficient utilization and sourcing.

The chemical compound, with the molecular formula C5H4ClNO2S and a molecular weight of 177.61, is primarily recognized for its role as an intermediate in the synthesis of Vonoprazan Fumarate. This pharmaceutical agent is known for its efficacy in managing gastric acid-related disorders. The purity of Pyridine-3-sulfonyl Chloride is a critical parameter, typically specified as ≥99.0%, ensuring that reactions proceed cleanly and the final product meets stringent pharmaceutical quality standards. This high purity is a key factor when considering where to buy Pyridine-3-sulfonyl Chloride.

As a moisture-sensitive compound, Pyridine-3-sulfonyl Chloride requires careful storage and handling. Suppliers often recommend storing it under inert gas in a cool, dry environment to maintain its reactivity and stability. This characteristic is vital for R&D scientists and production teams to consider when planning their workflows. The compound’s melting point is noted around 144°C, and its boiling point is approximately 284.162°C at atmospheric pressure, providing further insights into its physical behavior.

For those seeking to procure this chemical, identifying a dependable CAS 16133-25-8 supplier is essential. Whether you are a research institution or a large-scale pharmaceutical manufacturer, understanding the market and the competitive price of Pyridine-3-sulfonyl Chloride will guide your purchasing decisions. Working with a direct manufacturer can often provide better price points and more direct control over quality and delivery schedules. As a key intermediate, its consistent availability is crucial for uninterrupted production.

In summary, Pyridine-3-sulfonyl Chloride is more than just a chemical intermediate; it's a critical enabler for advanced pharmaceutical development. By understanding its properties and sourcing it from reputable manufacturers, you can confidently advance your research and production goals.