For any chemist, researcher, or procurement specialist dealing with chemical compounds, a thorough understanding of their properties and safe handling procedures is non-negotiable. 4-Fluorobenzhydrazide (CAS 456-06-4) is a valuable intermediate, and knowing its characteristics is key to its effective and safe use. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated manufacturer and supplier, provides crucial information to ensure our clients can confidently utilize this compound in their processes.

Chemical Profile of 4-Fluorobenzhydrazide

Molecular Formula: C7H7FN2O
Molecular Weight: 154.14 g/mol
Appearance: Typically an orange to light brown crystalline powder.
CAS Number: 456-06-4
Melting Point: Generally reported in the range of 162-166 °C. This solid state at room temperature is important for storage and handling.

The presence of the fluorine atom on the benzene ring influences the electron distribution within the molecule, contributing to its reactivity and the properties of compounds derived from it. The hydrazide group (-C(=O)NHNH2) is highly reactive and is a common functional group for forming new covalent bonds through reactions like condensation or cyclization.

Typical Applications in Synthesis

4-Fluorobenzhydrazide is primarily used as a:

  • Pharmaceutical Intermediate: It is a building block for synthesizing various heterocyclic compounds and complex organic molecules that form the basis of active pharmaceutical ingredients (APIs).
  • Agrochemical Intermediate: Similar to its role in pharmaceuticals, it can be used in the development of pesticides and herbicides.
  • Material Science Component: As mentioned previously, it's used in the synthesis of high-performance polymers, contributing unique properties derived from the fluorine atom.

When you buy 4-Fluorobenzhydrazide from a reputable manufacturer, you can expect detailed technical data sheets (TDS) and safety data sheets (SDS) that further elaborate on its chemical behavior and safe handling requirements.

Safe Handling and Storage Guidelines

Based on its typical hazard classifications (e.g., GHS07, Warning), 4-Fluorobenzhydrazide requires careful handling:

  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including gloves (nitrile or neoprene), safety glasses or goggles, and a lab coat. In dusty environments, respiratory protection may be necessary.
  • Ventilation: Handle the compound in a well-ventilated area or under a fume hood to minimize inhalation exposure.
  • Avoid Contact: Prevent contact with skin, eyes, and clothing. In case of contact, rinse thoroughly with water and seek medical attention if irritation persists.
  • Storage Conditions: Store in a cool, dry place, away from incompatible materials. Keep the container tightly sealed to prevent moisture absorption or contamination. Typically, storing it in a dark place at room temperature is recommended.

As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing not only high-quality 4-Fluorobenzhydrazide but also the necessary information for its safe and effective utilization. We encourage all our customers to review the provided SDS and TDS thoroughly. If you are looking to purchase this intermediate and require specific technical information or a quote, please contact our sales team.