In the pursuit of novel therapeutics and advancements in medicinal chemistry, the quality and availability of chemical intermediates are paramount. 1-Bromo-3-methoxypropane (CAS 36865-41-5), also known as 3-Bromopropyl Methyl Ether, has emerged as a particularly important building block, recognized for its pivotal role in the pharmaceutical sector. Its unique chemical characteristics make it an indispensable component in the synthesis of complex drug molecules.

Key Chemical Properties and Handling

This compound is typically supplied as a colorless to light yellow liquid, with a stated purity of ≥98.0%. Its molecular formula is C4H9BrO, and its molecular weight is approximately 153.02 g/mol. The presence of a bromine atom, acting as a good leaving group, is central to its reactivity. This feature allows 1-Bromo-3-methoxypropane to participate effectively in alkylation reactions, a cornerstone of many organic synthesis pathways. When considering its use, understanding its physical properties, such as its boiling point and flash point, is crucial for safe handling and storage. Given its classification as a flammable liquid and vapor, it requires storage in cool, well-ventilated areas away from ignition sources.

The Pharmaceutical Nexus: Brinzolamide Synthesis

The most well-documented and significant application of 1-Bromo-3-methoxypropane is its use as a key intermediate in the synthesis of Brinzolamide. Brinzolamide is a carbonic anhydrase inhibitor commonly formulated into eye drops to treat conditions such as ocular hypertension and open-angle glaucoma. The synthetic routes to Brinzolamide often involve incorporating the 3-methoxypropyl group, a task efficiently handled by 1-Bromo-3-methoxypropane. For pharmaceutical developers and contract manufacturing organizations (CMOs), securing a consistent supply of this high-purity intermediate is vital for meeting production demands and regulatory requirements. When you search for 'buy 1-bromo-3-methoxypropane', you are often looking for a reliable partner in the API intermediate supply chain.

Beyond Brinzolamide: Versatile Applications

While its role in Brinzolamide synthesis is prominent, the utility of 1-Bromo-3-methoxypropane extends to other areas of organic synthesis and medicinal chemistry. Its function as an alkylating agent allows it to be used in the preparation of various other complex organic molecules. Researchers can leverage its reactivity to introduce specific functional groups or to create ether linkages, which are common motifs in biologically active compounds. The demand for such versatile building blocks continues to grow as chemists explore new molecular entities for drug discovery and development.

Partnering with a Trusted Supplier

For companies that require 1-Bromo-3-methoxypropane, selecting a trustworthy manufacturer and supplier is critical. A reliable supplier not only guarantees product purity and batch-to-batch consistency but also offers competitive pricing and dependable delivery. Many leading chemical producers in China specialize in manufacturing high-quality pharmaceutical intermediates like 1-Bromo-3-methoxypropane. If you are a procurement manager or a research scientist looking for this essential compound, consider engaging with experienced manufacturers who can provide comprehensive technical data and customer support. We are a dedicated manufacturer and supplier committed to providing the high-purity intermediates necessary for your innovative projects.

Keywords for Innovation: 1-bromo-3-methoxypropane, pharmaceutical intermediate, Brinzolamide, organic synthesis, alkylation, medicinal chemistry, chemical supplier, drug discovery.