The chemical industry constantly evolves, with a focus on creating complex molecules that serve critical functions, particularly in pharmaceuticals. Understanding the synthesis and properties of key intermediates is vital for chemists and formulators. This article explores (1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one (CAS 79200-56-9), a valuable chiral building block commonly known as Vince lactam.

Vince lactam is a bicyclic γ-lactam with specific stereochemical configurations, making it an important component in asymmetric synthesis. Its chemical properties include a melting point typically ranging from 94-97°C and an appearance as off-white to beige crystals or crystalline powder. These characteristics are important for handling and formulation in research and production settings. The compound's high optical activity, indicated by its specific rotation, underscores its value as a chiral intermediate.

The synthesis of (1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one can be achieved through various routes, often involving enzymatic resolutions or sophisticated chemical transformations to ensure high enantiomeric purity. As a crucial intermediate, its primary application lies in the pharmaceutical sector. It is instrumental in the synthesis of antiviral drugs, such as Amino-peramivir, which is used to combat influenza infections. Furthermore, it serves as a precursor for carbocyclic sugar amines and nucleoside analogues, expanding its utility in the development of novel therapeutics. Researchers often look to buy this compound to initiate complex synthesis pathways.

For professionals in the chemical and pharmaceutical industries, identifying a reliable supplier or manufacturer for such specialized intermediates is key. Companies often seek cost-effective solutions and consistent quality, making manufacturers in regions like China attractive partners. Understanding the market dynamics, including the competitive price of Vince lactam, is essential for efficient procurement. By partnering with a reputable chemical provider, R&D teams can ensure they have access to the high-quality materials needed to drive innovation forward.

Exploring the synthesis, properties, and applications of (1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one reveals its indispensable role in modern pharmaceutical research. For those looking to procure this vital intermediate, focusing on quality and supply chain reliability will be paramount.