Understanding Ticagrelor Intermediates: The Role of 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine
The pharmaceutical industry relies heavily on precise chemical synthesis to produce life-saving medications. Among these, Ticagrelor stands out as a critical antiplatelet agent, widely prescribed to patients at risk of heart attack or stroke. The efficacy and availability of Ticagrelor are directly linked to the quality and reliable supply of its key intermediates. One such crucial component is 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine.
4,6-Dichloro-2-(propylthio)pyrimidin-5-amine, identified by its CAS number 145783-15-9, serves as a foundational building block in the multi-step synthesis of Ticagrelor. Its molecular structure, characterized by a pyrimidine ring with specific chlorine and propylthio substituents, is engineered to facilitate subsequent chemical reactions that ultimately form the active pharmaceutical ingredient (API) of Ticagrelor. The demand for high-quality Ticagrelor intermediates, such as this compound, is closely tied to the global prevalence of cardiovascular diseases, a growing concern that drives the need for effective preventative treatments.
The production of 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine requires meticulous attention to detail and adherence to stringent quality control measures. Manufacturers aim for high purity levels, typically assaying at 98.0% or above, to ensure predictable reaction outcomes and minimize impurities in the final drug product. The appearance, often described as a yellow to yellowish brown oily matter or solid, is a standard specification that indicates the compound's physical state upon production. Sourcing these critical intermediates from reliable manufacturers, particularly those with a strong presence in chemical production hubs like China, is paramount for pharmaceutical companies.
As a leading supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-purity 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine to support the global pharmaceutical supply chain. Our commitment extends beyond mere supply; we focus on ensuring the reliability and consistent quality of our products, understanding their vital role in patient health. By consistently meeting industry standards and exceeding customer expectations, we aim to be a preferred partner for companies involved in the synthesis of Ticagrelor and other vital medications. Investing in high-quality Ticagrelor intermediates is an investment in better patient outcomes and a stronger global healthcare system.
For those seeking a dependable supplier for 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine, focusing on purity and adherence to Good Manufacturing Practices (GMP) is essential. The consistent supply of such intermediates is crucial for uninterrupted production of life-saving drugs, directly impacting public health. NINGBO INNO PHARMCHEM CO.,LTD. is proud to contribute to this vital sector, providing the chemical foundations for therapeutic advancements.
4,6-Dichloro-2-(propylthio)pyrimidin-5-amine, identified by its CAS number 145783-15-9, serves as a foundational building block in the multi-step synthesis of Ticagrelor. Its molecular structure, characterized by a pyrimidine ring with specific chlorine and propylthio substituents, is engineered to facilitate subsequent chemical reactions that ultimately form the active pharmaceutical ingredient (API) of Ticagrelor. The demand for high-quality Ticagrelor intermediates, such as this compound, is closely tied to the global prevalence of cardiovascular diseases, a growing concern that drives the need for effective preventative treatments.
The production of 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine requires meticulous attention to detail and adherence to stringent quality control measures. Manufacturers aim for high purity levels, typically assaying at 98.0% or above, to ensure predictable reaction outcomes and minimize impurities in the final drug product. The appearance, often described as a yellow to yellowish brown oily matter or solid, is a standard specification that indicates the compound's physical state upon production. Sourcing these critical intermediates from reliable manufacturers, particularly those with a strong presence in chemical production hubs like China, is paramount for pharmaceutical companies.
As a leading supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-purity 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine to support the global pharmaceutical supply chain. Our commitment extends beyond mere supply; we focus on ensuring the reliability and consistent quality of our products, understanding their vital role in patient health. By consistently meeting industry standards and exceeding customer expectations, we aim to be a preferred partner for companies involved in the synthesis of Ticagrelor and other vital medications. Investing in high-quality Ticagrelor intermediates is an investment in better patient outcomes and a stronger global healthcare system.
For those seeking a dependable supplier for 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine, focusing on purity and adherence to Good Manufacturing Practices (GMP) is essential. The consistent supply of such intermediates is crucial for uninterrupted production of life-saving drugs, directly impacting public health. NINGBO INNO PHARMCHEM CO.,LTD. is proud to contribute to this vital sector, providing the chemical foundations for therapeutic advancements.
Perspectives & Insights
Alpha Spark Labs
“The demand for high-quality Ticagrelor intermediates, such as this compound, is closely tied to the global prevalence of cardiovascular diseases, a growing concern that drives the need for effective preventative treatments.”
Future Pioneer 88
“The production of 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine requires meticulous attention to detail and adherence to stringent quality control measures.”
Core Explorer Pro
“0% or above, to ensure predictable reaction outcomes and minimize impurities in the final drug product.”