In the dynamic field of chemical research and development (R&D), the availability of versatile and high-quality chemical intermediates is crucial for innovation. Methyl L-Tyrosinate Hydrochloride (H-Tyr-OMe·HCl), identified by CAS number 3417-91-2, stands out as a compound with considerable utility, bridging amino acid chemistry with broader organic synthesis applications.

Understanding Methyl L-Tyrosinate Hydrochloride

This derivative of L-tyrosine is more than just a simple amino acid ester. Its structure, a methyl ester of tyrosine coupled with a hydrochloride salt, provides specific reactivity and stability advantages. Typically presented as a white to off-white crystalline powder, its purity, often exceeding 98% via HPLC, is a key factor for its use in R&D, where precision is paramount. The chemical formula C10H14ClNO3 and molecular weight of 231.68 g/mol define its properties, making it a well-characterized reagent.

R&D Applications: Beyond Basic Peptide Synthesis

While its primary use is in peptide synthesis, where it acts as a protected tyrosine residue for incorporation into peptide chains, the versatility of H-Tyr-OMe HCl extends much further in R&D:

  • Organic Synthesis: Researchers utilize it as a chiral building block for synthesizing complex organic molecules, including potential drug candidates, specialty chemicals, and functional materials. The presence of both an amino group and a protected carboxylic acid (as the methyl ester) allows for a variety of chemical transformations.
  • Medicinal Chemistry: In drug discovery programs, it serves as a scaffold for generating libraries of compounds. Modifications on the phenolic hydroxyl group or the amino terminus can lead to novel molecules with targeted biological activities.
  • Biochemical Studies: Its role as a precursor or derivative of tyrosine makes it useful in studies investigating tyrosine metabolism, protein phosphorylation, and related biochemical pathways.
  • Method Development: As a standard compound with well-defined properties, it is often used in developing and validating new synthetic methodologies or analytical techniques in organic chemistry and chromatography.

Sourcing for Research: Quality and Accessibility

For R&D professionals, the ability to easily buy small to moderate quantities of high-purity Methyl L-Tyrosinate Hydrochloride is critical. Reliable suppliers, often specializing in research chemicals and fine chemicals, are essential partners. These suppliers typically offer detailed product information, including CoAs, and ensure timely delivery, even for smaller research-scale orders. When sourcing, focusing on suppliers with a broad catalog of amino acid derivatives can streamline the procurement process for related compounds.

Conclusion

Methyl L-Tyrosinate Hydrochloride is a valuable tool in the R&D chemist's arsenal. Its utility extends beyond peptide synthesis into diverse areas of organic synthesis and medicinal chemistry. Ensuring access to high-purity material from a dependable manufacturer or supplier is key to driving innovation and advancing research projects.